Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.59 |
| ▸ | ACE | P12821 | 7/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.56 |
| ▸ | FPR2 | P25090 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CPA1 | P15085 | 2/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427433 | 1.00 | MME (0.59) | MMEACENPSR1NAALAD2FPR2 | |
| SCHEMBL10504767 | 0.84 | ITGB3 (0.65) | MMEACENPSR1NAALAD2ECE1 | |
| SCHEMBL6316065 | 0.84 | MME (0.61) | MMEACENPSR1NAALAD2FPR2 | |
| SCHEMBL1477208 | 0.84 | ACE (0.62) | MMEACENPSR1NAALAD2ECE1 | |
| SCHEMBL4144668 | 0.84 | ITGB3 (0.65) | MMEACENPSR1NAALAD2ECE1 | |
| SCHEMBL6316057 | 0.84 | FPR2 (0.61) | MMEACENPSR1NAALAD2FPR2 | |
| SCHEMBL4144665 | 0.84 | ITGB3 (0.65) | MMEACENPSR1NAALAD2ECE1 | |
| SCHEMBL14503222 | 0.84 | ACE (0.62) | MMEACENPSR1NAALAD2ECE1 | |
| SCHEMBL21777173 | 0.84 | MME (0.61) | MMEACENPSR1NAALAD2FPR2 | |
| SCHEMBL28593577 | 0.84 | ACE (0.62) | MMEACENPSR1NAALAD2ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212056-B1 | METHODS AND COMPOSITIONS FOR BISUBSTRATE INHIBITORS OF ACETYLTRANSFERASES | US GOV HEALTH & HUMAN SERV (US) | 2005-12-07 | — | — | EP | disclosed |
| US-5466801-A | Process for the preparation of 3-, 6-substituted 2,5-morpholinediones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-11-14 | — | — | US | disclosed |
| EP-0322154-B1 | Bioabsorbable polydepsipeptides, their preparation and use | PFIZER (US) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994003441-A1 | PROCESS FOR THE PREPARATION OF 3-, 6-SUBSTITUTED 2,5-MORPHOLINEDIONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-02-17 | — | — | WO | disclosed |
| US-4994551-A | Sutures | PFIZER INC. (US) | 1991-02-19 | — | — | US | disclosed |
| US-4916209-A | SURGICAL SUTURES AND CLIPS | PFIZER INC. (US) | 1990-04-10 | — | — | US | disclosed |
| EP-0322154-A2 | Bioabsorbable polydepsipeptides, their preparation and use | PFIZER INC. (US) | 1989-06-28 | — | — | EP | disclosed |