Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.61 |
| ▸ | ACE | P12821 | 7/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.58 |
| ▸ | ECE1 | P42892 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CPA1 | P15085 | 2/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.55 |
| ▸ | FPR2 | P25090 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26985720 | 1.00 | MME (0.61) | MMEACENPSR1NAALAD2ECE1 | |
| SCHEMBL16079952 | 1.00 | MME (0.61) | MMEACENPSR1NAALAD2ECE1 | |
| SCHEMBL24642633 | 0.88 | MME (0.52) | MMEACENPSR1NAALAD2ECE1 | |
| SCHEMBL15083422 | 0.86 | HPGDS (0.56) | — | |
| SCHEMBL1991725 | 0.86 | ACE (0.62) | MMEACENAALAD2L3MBTL1CPA1 | |
| SCHEMBL23227492 | 0.86 | ACE (0.63) | MMEACENPSR1NAALAD2ECE1 | |
| SCHEMBL1991726 | 0.86 | ACE (0.62) | MMEACENAALAD2L3MBTL1CPA1 | |
| SCHEMBL14503222 | 0.86 | ACE (0.62) | MMEACENPSR1NAALAD2ECE1 | |
| SCHEMBL10504767 | 0.86 | ITGB3 (0.65) | MMEACENPSR1NAALAD2ECE1 | |
| SCHEMBL4144668 | 0.86 | ITGB3 (0.65) | MMEACENPSR1NAALAD2ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180214556-A1 | AQUEOUS COMPOSITION COMPRISING AT LEAST ONE PROTEIN AND ONE SOLUBILIZING AGENT, PREPARATION THEREOF AND USES THEREOF | ADOCIA (FR) | 2018-08-02 | — | — | US | claimed |
| US-20150335751-A1 | AQEOUS COMPOSITION COMPRISING AT LEAST ONE PROTEIN AND ONE SOLUBILIZING AGENT, PREPARATION THEREOF AND USES THEREOF | ADOCIA (FR) | 2015-11-26 | — | — | US | claimed |
| WO-2015173377-A1 | AQUEOUS COMPOSITION COMPRISING AT LEAST ONE PROTEIN AND ONE SOLUBILIZING AGENT, PREPARATION THEREOF AND USES THEREOF | ADOCIA (FR) | 2015-11-19 | — | — | WO | claimed |
| US-6906058-B2 | 1,5-Benzothiazepines and their use as hypolipidaemics | ASTRAZENECA AB (SE) | 2005-06-14 | — | — | US | claimed |
| EP-1263747-B1 | 1,5-BENZOTHIAZEPINES AND THEIR USE AS HYPOLIPIDAEMICS | ASTRAZENECA AB (SE) | 2004-11-24 | — | — | EP | claimed |
| US-20030166927-A1 | 1,5-Benzothiazepines and their use as hypolipidaemics | ALBIREO AB (SE) | 2003-09-04 | — | — | US | claimed |
| EP-1263747-A1 | 1,5-BENZOTHIAZEPINES AND THEIR USE AS HYPOLIPIDAEMICS | AstraZeneca AB (SE) | 2002-12-11 | — | — | EP | claimed |
| WO-2001066533-A1 | 1,5-BENZOTHIAZEPINES AND THEIR USE AS HYPOLIPIDAEMICS | ASTRAZENECA AB (SE) | 2001-09-13 | — | — | WO | claimed |
| WO-2024008941-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2024-01-11 | — | — | WO | disclosed |
| CN-112322691-A | Rapid screening method and application of immune regulation activity of algal polysaccharide | 华南农业大学 | 2021-02-05 | — | — | CN | disclosed |
| US-20180214556-A1 | AQUEOUS COMPOSITION COMPRISING AT LEAST ONE PROTEIN AND ONE SOLUBILIZING AGENT, PREPARATION THEREOF AND USES THEREOF | ADOCIA (FR) | 2018-08-02 | — | — | US | disclosed |
| US-20180214556-A1 | AQUEOUS COMPOSITION COMPRISING AT LEAST ONE PROTEIN AND ONE SOLUBILIZING AGENT, PREPARATION THEREOF AND USES THEREOF | ADOCIA (FR) | 2018-08-02 | — | — | US | disclosed |
| US-20180214556-A1 | AQUEOUS COMPOSITION COMPRISING AT LEAST ONE PROTEIN AND ONE SOLUBILIZING AGENT, PREPARATION THEREOF AND USES THEREOF | ADOCIA (FR) | 2018-08-02 | — | — | US | disclosed |
| US-20150335751-A1 | AQEOUS COMPOSITION COMPRISING AT LEAST ONE PROTEIN AND ONE SOLUBILIZING AGENT, PREPARATION THEREOF AND USES THEREOF | ADOCIA (FR) | 2015-11-26 | — | — | US | disclosed |
| US-20150335751-A1 | AQEOUS COMPOSITION COMPRISING AT LEAST ONE PROTEIN AND ONE SOLUBILIZING AGENT, PREPARATION THEREOF AND USES THEREOF | ADOCIA (FR) | 2015-11-26 | — | — | US | disclosed |
| US-20150335751-A1 | AQEOUS COMPOSITION COMPRISING AT LEAST ONE PROTEIN AND ONE SOLUBILIZING AGENT, PREPARATION THEREOF AND USES THEREOF | ADOCIA (FR) | 2015-11-26 | — | — | US | disclosed |
| WO-2015173377-A1 | AQUEOUS COMPOSITION COMPRISING AT LEAST ONE PROTEIN AND ONE SOLUBILIZING AGENT, PREPARATION THEREOF AND USES THEREOF | ADOCIA (FR) | 2015-11-19 | — | — | WO | disclosed |
| US-6906058-B2 | 1,5-Benzothiazepines and their use as hypolipidaemics | ASTRAZENECA AB (SE) | 2005-06-14 | — | — | US | disclosed |
| EP-1263747-B1 | 1,5-BENZOTHIAZEPINES AND THEIR USE AS HYPOLIPIDAEMICS | ASTRAZENECA AB (SE) | 2004-11-24 | — | — | EP | disclosed |
| US-20030166927-A1 | 1,5-Benzothiazepines and their use as hypolipidaemics | ALBIREO AB (SE) | 2003-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180214556-A1 | AQUEOUS COMPOSITION COMPRISING AT LEAST ONE PROTEIN AND ONE SOLUBILIZING AGENT, PREPARATION THEREOF AND USES THEREOF | SET, SON, S100A6 | MME 913/4885ACE 819/4885NPSR1 3027/4885 |
| US-20030166927-A1 | 1,5-Benzothiazepines and their use as hypolipidaemics | SLC10A2, SLC10A1, LCAT | MME 2753/4885ACE 1590/4885NPSR1 1594/4885 |
| US-20150335751-A1 | AQEOUS COMPOSITION COMPRISING AT LEAST ONE PROTEIN AND ONE SOLUBILIZING AGENT, PREPARATION THEREOF AND USES THEREOF | ATIC, SON, MAX | MME 199/4885ACE 525/4885NPSR1 3046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.