Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.47 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KDM5C | P41229 | 3/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.42 |
| ▸ | KDM6B | O15054 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627376 | 0.89 | ALDH1A1 (0.35) | LMNAABCC4MAPTTSHRCYP2D6 | |
| SCHEMBL11870573 | 0.85 | SLC22A6 (0.52) | LMNAGABRR1ABCC4MAPTTSHR | |
| SCHEMBL7698896 | 0.85 | MAPT (0.58) | LMNAABCC4MAPTTSHRCYP2D6 | |
| Succinic Acid SCHEMBL5161622 | 0.83 | LMNA (0.53) | EGLN1LMNAALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL3962895 | 0.78 | LMNA (0.53) | EGLN1LMNAALKBH5SUCNR1GABRR1 | |
| SCHEMBL8384603 | 0.78 | LMNA (0.53) | EGLN1LMNAALKBH5SUCNR1GABRR1 | |
| SCHEMBL3628147 | 0.77 | TSHR (0.40) | LMNATSHRALDH1A1 | |
| SCHEMBL3627630 | 0.77 | ALDH1A1 (0.50) | EGLN1LMNAKDM4EKDM5CPHF8 | |
| SCHEMBL28717818 | 0.77 | TDP1 (0.43) | TSHRCYP2D6MAPK1ALDH1A1FFAR3 | |
| SCHEMBL16653999 | 0.77 | TSHR (0.34) | TSHRCYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142894-B1 | Volatile precursors for deposition of metals and metal-containing films | AIR PROD & CHEM (US) | 2005-01-12 | — | — | EP | disclosed |
| US-6818783-B2 | HOMOLOGOUS EIGHT MEMBERED RING COMPOUNDS HAVING A METAL, SUCH AS COPPER, REVERSIBLY BOUND IN THE RING AND CONTAINING CARBON, NITROGEN, SILICON AND/OR OTHER METALS. | AIR PRODUCTS AND CHEMICALS, INC. | 2004-11-16 | — | — | US | disclosed |
| US-20040215030-A1 | Precursors for metal containing films | VERSUM MATERIALS US, LLC | 2004-10-28 | — | — | US | disclosed |
| EP-1471568-A1 | Precursors for metal containing films | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2004-10-27 | — | — | EP | disclosed |
| US-20030135061-A1 | Volatile precursors for deposition of metals and metal-containing films | VERSUM MATERIALS US, LLC | 2003-07-17 | — | — | US | disclosed |
| US-20020013487-A1 | Volatile precursors for deposition of metals and metal-containing films | VERSUM MATERIALS US, LLC | 2002-01-31 | — | — | US | disclosed |
| EP-1142894-A2 | Volatile precursors for deposition of metals and metal-containing films | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5091559-A | Process for the preparation of alkyl 4-oxobutyrate and its acetals | QUANTUM CHEMICAL CORPORATION (US) | 1992-02-25 | — | — | US | disclosed |
| US-4931219-A | SPIRO/BENZIDOLINE/PYRIDOBENZOXAZINE AND SPIRO/BENZIDOLINE/ NAPHTHOXAZINE COMPOUNDS; OPTICAL LENSES | PPG INDUSTRIES, INC. (US) | 1990-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013487-A1 | Volatile precursors for deposition of metals and metal-containing films | SOD1, C1R, C5 | EGLN1 3931/4885LMNA 837/4885ALKBH5 200/4885 |
| US-20030135061-A1 | Volatile precursors for deposition of metals and metal-containing films | SOD1, C1R, C5 | EGLN1 3792/4885LMNA 695/4885ALKBH5 172/4885 |
| US-20040215030-A1 | Precursors for metal containing films | TBL3, TBL2, TNNI3 | EGLN1 3662/4885LMNA 205/4885ALKBH5 834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.