Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6302926 | 0.91 | PARP1 (0.36) | CTSKKDM4EALDH1A1RCE1MAPT | |
| SCHEMBL6304809 | 0.86 | MAPT (0.39) | KDM4EALDH1A1RCE1MAPTPLA2G1B | |
| SCHEMBL5464875 | 0.82 | MAPT (0.34) | KDM4EALDH1A1RCE1MAPTPLA2G1B | |
| SCHEMBL5473212 | 0.82 | MAPT (0.40) | KDM4EALDH1A1RCE1MAPTNPSR1 | |
| SCHEMBL5467225 | 0.81 | MAPT (0.39) | KDM4EALDH1A1RCE1MAPTNPSR1 | |
| SCHEMBL7092669 | 0.81 | CTSS (0.34) | CTSKKDM4EALDH1A1RCE1MAPT | |
| SCHEMBL7704943 | 0.80 | ALDH1A1 (0.43) | CTSKALDH1A1MAPTHPGDXBP1 | |
| SCHEMBL5472786 | 0.80 | MAPT (0.41) | CTSKKDM4EALDH1A1RCE1MAPT | |
| SCHEMBL5465748 | 0.80 | DRD2 (0.37) | KDM4EMAPTNPSR1 | |
| SCHEMBL7095640 | 0.79 | ALDH1A1 (0.37) | KDM4EALDH1A1RCE1MAPTPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841550-B1 | Benzoxazine and benzothiazine derivatives and their use in medicines | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-11 | — | — | US | disclosed |
| EP-1114037-B1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN MEDICINES | SCHERING AG (DE) | 2004-05-12 | — | — | EP | disclosed |