Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572187 | 0.81 | ALDH1A1 (0.81) | SMN1; SMN2HTTHPGDALDH1A1RAB9A | |
| SCHEMBL4339089 | 0.78 | PAX8 (0.78) | SMN1; SMN2HTTHPGDALDH1A1RAB9A | |
| SCHEMBL3455416 | 0.78 | HPGD (0.76) | SMN1; SMN2HTTHPGDALDH1A1RAB9A | |
| SCHEMBL12301885 | 0.78 | NPC1 (0.76) | SMN1; SMN2HTTHPGDALDH1A1RAB9A | |
| SCHEMBL12301886 | 0.78 | ALDH1A1 (0.76) | SMN1; SMN2HTTALDH1A1RAB9ANPC1 | |
| SCHEMBL5183187 | 0.77 | HPGD (0.74) | SMN1; SMN2HTTHPGDALDH1A1RAB9A | |
| SCHEMBL26646791 | 0.77 | HPGD (0.73) | SMN1; SMN2HTTHPGDALDH1A1RAB9A | |
| SCHEMBL12882984 | 0.76 | TSHR (1.00) | SMN1; SMN2HTTALDH1A1L3MBTL1TSHR | |
| SCHEMBL13762071 | 0.76 | ALDH1A1 (0.72) | SMN1; SMN2HTTHPGDALDH1A1RAB9A | |
| SCHEMBL18698019 | 0.75 | HPGD (0.70) | SMN1; SMN2HTTHPGDALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175155-A4 | METHOD FOR REDUCING A SUSCEPTIBILITY TO TUMOR FORMATION INDUCED BY 3-DEOXYGLUCOSONE AND PRECURSORS THEREOF | FOX CHASE CANCER CT (US) | 2005-10-19 | — | — | EP | disclosed |
| EP-1175155-A1 | METHOD FOR REDUCING A SUSCEPTIBILITY TO TUMOR FORMATION INDUCED BY 3-DEOXYGLUCOSONE AND PRECURSORS THEREOF | FOX CHASE CANCER CENTER (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000062626-A1 | METHOD FOR REDUCING A SUSCEPTIBILITY TO TUMOR FORMATION INDUCED BY 3-DEOXYGLUCOSONE AND PRECURSORS THEREOF | FOX CHASE CANCER CENTER (US) | 2000-10-26 | — | — | WO | disclosed |