SCHEMBL6428520

SCHEMBL6428520

O=C(C[C@@H](CCCC1CCCCC1)c1nc(Cc2ccncc2)no1)NO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 20/20 1.00
MMP1 P03956 1/20 0.66
MMP3 P08254 1/20 0.66
MMP13 P45452 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27586624 1.00 BMP1 (1.00) BMP1MMP1MMP3MMP13
SCHEMBL27567184 0.89 BMP1 (0.81) BMP1MMP1MMP3MMP13
SCHEMBL6428235 0.89 BMP1 (0.81) BMP1MMP1MMP3MMP13
SCHEMBL27567365 0.89 BMP1 (1.00) BMP1
SCHEMBL6429290 0.89 BMP1 (1.00) BMP1
SCHEMBL14502749 0.85 BMP1 (1.00) BMP1MMP1MMP3MMP13
SCHEMBL7136605 0.85 BMP1 (1.00) BMP1
SCHEMBL6598983 0.85 BMP1 (1.00) BMP1
SCHEMBL6429350 0.84 BMP1 (1.00) BMP1
SCHEMBL27567386 0.84 BMP1 (0.73) BMP1MMP1MMP3MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6888022-B2 Methods and compounds for inhibiting β-amyloid peptide release and/or its synthesis ATHENA NEUROSCIENCES, INC. (US) 2005-05-03 US claimed
US-5117057-A Insecticidal N' substituted-N-N'-disubstituted-hydrazines ROHM AND HAAS COMPANY (US) 1992-05-26 US claimed
EP-0286746-B1 INSECTICIDAL N-(OPTIONALLY SUBSTITUTED) - N'-SUBSTITUTED-N,N'-DISUBSTITUTED- HYDRAZINES ROHM AND HAAS COMPANY (US) 1991-02-27 EP claimed
EP-0286746-A1 Insecticidal N-(optionally substituted) - N'-substituted-N,N'-disubstituted- hydrazines ROHM AND HAAS COMPANY (US) 1988-10-19 EP claimed
EP-3339286-A1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-06-27 EP disclosed
EP-2427426-B1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-02-07 EP disclosed
WO-2013092942-A1 USE OF AMINOBENZAMIDE DERIVATIVES FOR CONTROLLING ANIMAL PARASITES SYNGENTA PARTICIPATIONS AG (CH) 2013-06-27 WO disclosed
US-20120295907-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, LLC (US) 2012-11-22 US disclosed
US-6897306-B2 3-heterocyclylpropanohydroxamic acids PFIZER PRODUCTS, INC. (US) 2005-05-24 US disclosed
EP-1240152-B1 OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LTD (GB) 2004-12-08 EP disclosed
US-20030119807-A1 3-Heterocyclylpropanohydroxamic acids BAILEY SIMON (US) 2003-06-26 US disclosed
US-6448278-B2 ANTISCARRING AGENT PFIZER INC. 2002-09-10 US disclosed
US-4994363-A Silver halide light-sensitive material containing a compound releasing a photographically useful group FUJI PHOTO FILM CO., LTD. (JP) 1991-02-19 US disclosed
US-H830-H CONTAINING A DESILVERING ACCELERATOR RELEASING COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-10-02 US disclosed
US-4956263-A BLACKAND WHITE PHOTOGRAPHIC FILM CONTAINING CONTAINING A HYDRAZINE DERIVATIVE; HIGH CONTRAST; DAYLIGHT USE; ANTISOILANTS; SAFELIGHT SAFETY FUJI PHOTO FILM CO., LTD. (JP) 1990-09-11 US disclosed
US-H817-H Photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-09-04 US disclosed
US-4921785-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-05-01 US disclosed
US-4916047-A POLYMERIC COMPOUND RELEASING USEFUL GROUP BY REDOX PROCESS TRIGGERED BY REDUCING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1990-04-10 US disclosed
US-4840887-A USEFUL GROUP RELEASED BY CLEAVAGE BETWEEN SULFONYL GROUP AND A NITROGEN, SULFUR OR OXYGEN ATOM; STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1989-06-20 US disclosed
EP-0306833-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-03-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120295907-A1 INSECTICIDAL COMPOUNDS ACHE, AADAC, BCHE BMP1 4364/4885MMP1 2875/4885MMP3 4056/4885
US-20030119807-A1 3-Heterocyclylpropanohydroxamic acids CPA1, MMP1, PREP BMP1 79/4885MMP1 2/4885MMP3 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.