Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 11/20 | 0.71 |
| ▸ | RGS8 | P57771 | 11/20 | 0.71 |
| ▸ | GSK3B | P49841 | 4/20 | 0.54 |
| ▸ | GSK3A | P49840 | 3/20 | 0.54 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | RGS16 | O15492 | 1/20 | 0.37 |
| ▸ | RGS19 | P49795 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13517517 | 0.83 | RGS4 (1.00) | RGS4RGS8GSK3BGSK3AKAT2B | |
| SCHEMBL14941895 | 0.81 | RGS4 (0.70) | RGS4RGS8GSK3BGSK3AKAT2B | |
| SCHEMBL14950545 | 0.80 | RGS4 (0.69) | RGS4RGS8GSK3BGSK3AKAT2B | |
| SCHEMBL14950548 | 0.71 | RGS4 (0.57) | RGS4RGS8GSK3BGSK3AKAT2B | |
| SCHEMBL3383077 | 0.70 | GSK3A (1.00) | RGS4RGS8GSK3BGSK3AFAAH | |
| SCHEMBL22349820 | 0.65 | GSK3A (0.44) | GSK3BGSK3AFAAHMGLL | |
| SCHEMBL3384015 | 0.63 | GSK3B (0.71) | RGS4RGS8GSK3BGSK3APRKCA | |
| SCHEMBL4617337 | 0.63 | IDO1 (0.42) | GSK3BGSK3A | |
| SCHEMBL6426900 | 0.62 | GSK3B (0.59) | RGS4RGS8GSK3BGSK3A | |
| SCHEMBL15396388 | 0.62 | PGR (0.51) | GSK3BGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005024755-A2 | MEDICAMENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS OR DIABETES | DECIPHERA PHARMACEUTICALS, LLC. (US) | 2005-03-17 | — | — | WO | disclosed |