Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.59 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.57 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.57 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.56 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.54 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.54 |
| ▸ | TARS1 | P26639 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499233 | 0.89 | ADORA2A (0.64) | — | |
| SCHEMBL3499237 | 0.89 | ADORA2A (0.64) | — | |
| SCHEMBL8164945 | 0.87 | ADORA3 (0.54) | ADORA3ADORA1 | |
| SCHEMBL2033392 | 0.86 | TARS1 (0.60) | ADORA3ADORA1PRMT5WDR77P2RY12 | |
| SCHEMBL2056705 | 0.86 | ADORA3 (0.60) | ADORA3ADORA1PRMT5WDR77P2RY12 | |
| SCHEMBL9413282 | 0.85 | ADORA3 (0.74) | ADORA3ADORA1 | |
| SCHEMBL9620148 | 0.85 | ADORA3 (0.74) | ADORA3ADORA1 | |
| SCHEMBL6661320 | 0.83 | ADORA3 (0.67) | ADORA3ADORA1PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL6661329 | 0.83 | ADORA3 (0.67) | ADORA3ADORA1 | |
| SCHEMBL2761074 | 0.83 | MEN1 (0.66) | ADORA3ADORA1PRKAG1PRKAA1PRKAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176045-A1 | SNP discriminatory siRNA | DHARMACON, INC. (US) | 2005-08-11 | — | — | US | disclosed |