Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.60 |
| ▸ | TARS1 | P26639 | 2/20 | 0.57 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.56 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.52 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.52 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.52 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.52 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692894 | 0.91 | PRMT5 (0.60) | PRMT5WDR77 | |
| SCHEMBL2033392 | 0.88 | TARS1 (0.60) | ADORA3TARS1PRMT5WDR77ADORA1 | |
| SCHEMBL6429185 | 0.86 | ADORA3 (0.66) | ADORA3TARS1PRMT5WDR77ADORA1 | |
| SCHEMBL29047902 | 0.83 | ADORA2A (0.60) | — | |
| SCHEMBL29047905 | 0.83 | ADORA2A (0.60) | — | |
| SCHEMBL5155877 | 0.83 | TARS1 (0.62) | TARS1PRMT5WDR77ADORA1DOT1L | |
| SCHEMBL2988353 | 0.81 | P2RY12 (0.68) | TARS1ADORA1PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL8161496 | 0.81 | PRKAG1 (0.56) | PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL6661329 | 0.81 | ADORA3 (0.67) | ADORA3ADORA1 | |
| SCHEMBL9413282 | 0.80 | ADORA3 (0.74) | ADORA3ADORA1DOT1LPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7901892-B2 | Methods and compositions for determining the purity of chemically synthesized nucleic acids | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-03-08 | — | — | US | disclosed |