Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.44 |
| ▸ | IDH2 | P48735 | 1/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.40 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269757 | 0.82 | KCNH3 (0.41) | KCNH3CAMK2DEHMT2EHMT1 | |
| SCHEMBL5029195 | 0.81 | IDH2 (0.57) | IDH2EHMT2EHMT1 | |
| SCHEMBL4832446 | 0.77 | GALR1 (0.42) | EHMT2EHMT1 | |
| SCHEMBL5552484 | 0.76 | EHMT2 (0.47) | EHMT2EHMT1POLB | |
| SCHEMBL13347230 | 0.74 | KCNH3 (0.57) | KCNH3 | |
| SCHEMBL4836212 | 0.74 | BCL6 (0.50) | KCNH3EHMT2EHMT1 | |
| SCHEMBL4829068 | 0.73 | BCL6 (0.46) | EHMT2EHMT1 | |
| SCHEMBL6819368 | 0.72 | EHMT2 (0.38) | IDH2EHMT2EHMT1ABL1BTK | |
| SCHEMBL14421529 | 0.72 | EHMT2 (0.46) | KCNH3EHMT2EHMT1 | |
| SCHEMBL4838198 | 0.71 | RPS6KA3 (0.36) | KCNH3IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050227983-A1 | Triazine compounds and their analogs, compositions, and methods | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227983-A1 | Triazine compounds and their analogs, compositions, and methods | MYLK, SMAD3, GID4 | KCNH3 4434/4885TBK1 348/4885IDH2 3730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.