Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 16/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5409612 | 0.86 | ADORA1 (0.63) | ADORA1ADORA3SLC28A1ADORA2AADORA2B | |
| SCHEMBL5391634 | 0.83 | ADORA1 (0.56) | ADORA1ADORA3SLC28A1ADORA2AADORA2B | |
| SCHEMBL6427736 | 0.81 | LMNA (0.46) | — | |
| SCHEMBL5401465 | 0.75 | ADORA1 (0.50) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL5396369 | 0.75 | ADORA1 (0.50) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL14593744 | 0.75 | ADORA1 (0.50) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL6448022 | 0.73 | CCNA2 (0.48) | ADORA1 | |
| SCHEMBL12226387 | 0.73 | ADORA3 (0.71) | ADORA1ADORA3ADORA2AADORA2BSLC29A1 | |
| SCHEMBL15080480 | 0.73 | ADORA3 (0.71) | ADORA1ADORA3ADORA2AADORA2BSLC29A1 | |
| SCHEMBL12200105 | 0.73 | ADORA3 (0.71) | ADORA1ADORA3ADORA2AADORA2BSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590359-A2 | PARTIAL AND FULL AGONISTS OF A sb 1 /sb ADENOSINE RECEPTORS | CV Therapeutics Inc. (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004069185-A2 | PARTIAL AND FULL AGONISTS OF A1 ADENOSINE RECEPTORS | CV THERAPEUTICS INC. (US) | 2004-08-19 | — | — | WO | disclosed |