Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TYMP | P19971 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3163915 | 0.82 | LMNA (0.53) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL13970745 | 0.82 | LMNA (0.53) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL14615870 | 0.82 | TYMP (0.50) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL3163908 | 0.82 | LMNA (0.53) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL20059072 | 0.82 | TYMP (0.50) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL6429891 | 0.81 | ADORA1 (0.55) | — | |
| SCHEMBL5389026 | 0.79 | LMNA (0.46) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL5389035 | 0.79 | LMNA (0.46) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL14593730 | 0.79 | LMNA (0.46) | LMNATYMPSTING1ABCB1P2RX3 | |
| SCHEMBL7699396 | 0.79 | LMNA (0.45) | LMNATYMPSTING1ABCB1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590359-A2 | PARTIAL AND FULL AGONISTS OF A sb 1 /sb ADENOSINE RECEPTORS | CV Therapeutics Inc. (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004069185-A2 | PARTIAL AND FULL AGONISTS OF A1 ADENOSINE RECEPTORS | CV THERAPEUTICS INC. (US) | 2004-08-19 | — | — | WO | disclosed |