Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 12/20 | 0.62 |
| ▸ | BACE1 | P56817 | 5/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882998 | 0.76 | PGR (1.00) | PGR | |
| SCHEMBL79962 | 0.73 | PGR (0.60) | PGR | |
| SCHEMBL3880052 | 0.70 | PGR (0.76) | PGR | |
| SCHEMBL80304 | 0.65 | AHR (0.42) | PGRBACE1 | |
| SCHEMBL12077088 | 0.65 | CYP1A1 (0.55) | PGRGRM5 | |
| SCHEMBL3879414 | 0.64 | PGR (1.00) | PGR | |
| SCHEMBL202404 | 0.63 | ALDH1A1 (0.61) | PGRGRM5 | |
| SCHEMBL16894215 | 0.62 | KIF11 (0.57) | PGRGRM5 | |
| SCHEMBL25014569 | 0.62 | CYP1A1 (0.65) | PGR | |
| SCHEMBL509576 | 0.62 | ALDH1A1 (0.58) | PGRGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515725-A4 | USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS | WYETH CORP (US) | 2005-09-21 | — | — | EP | disclosed |
| EP-1515725-A2 | USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS | Wyeth (US) | 2005-03-23 | — | — | EP | disclosed |
| WO-2004000801-A2 | USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS | WYETH (US) | 2003-12-31 | — | — | WO | disclosed |