SCHEMBL6430715

SCHEMBL6430715

NC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)NO)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 20/20 1.00
PDE4A P27815 1/20 1.00
PDE4B Q07343 1/20 1.00
PDE4C Q08493 1/20 1.00
PDE4D Q08499 1/20 1.00
MMP3 P08254 1/20 0.76
MMP2 P08253 3/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL6429390 0.99 BMP1 (0.98) BMP1PDE4APDE4BPDE4CPDE4D
SCHEMBL6428262 0.88 BMP1 (0.78) BMP1PDE4APDE4BPDE4CPDE4D
SCHEMBL27567224 0.88 BMP1 (0.78) BMP1PDE4APDE4BPDE4CPDE4D
SCHEMBL6428360 0.88 BMP1 (1.00) BMP1PDE4APDE4BPDE4CPDE4D
SCHEMBL5408264 0.87 BMP1 (0.78) BMP1PDE4APDE4BPDE4CPDE4D
SCHEMBL6429362 0.87 BMP1 (1.00) BMP1PDE4APDE4BPDE4CPDE4D
SCHEMBL6428452 0.87 BMP1 (1.00) BMP1PDE4APDE4BPDE4CPDE4D
SCHEMBL6428730 0.86 BMP1 (0.82) BMP1PDE4APDE4BPDE4CPDE4D
SCHEMBL14502749 0.86 BMP1 (1.00) BMP1PDE4APDE4BPDE4CPDE4D
SCHEMBL5404106 0.86 BMP1 (1.00) BMP1PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608977-A1 COMPOSITIONS AND METHODS FOR ACCELERATED PRODUCTION OF THYMIC CELLS FROM PLURIPOTENT STEM CELLS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2025-09-03 EP claimed
CN-119162082-A Method for preparing extrahepatic vesicles/apoptotic vesicles by inducing fibroblasts to be directly reprogrammed into liver-like cells and application of method 中国人民解放军海军军医大学 2024-12-20 CN claimed
CN-118308295-B Additive, culture medium and method for promoting cell to produce collagen 上海遇见味来生物技术有限公司 2024-08-27 CN claimed
CN-118308295-A Additive, culture medium and method for promoting cell to produce collagen 上海遇见味来生物技术有限公司 2024-07-09 CN claimed
WO-2024091676-A1 COMPOSITIONS AND METHODS FOR ACCELERATED PRODUCTION OF THYMIC CELLS FROM PLURIPOTENT STEM CELLS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2024-05-02 WO claimed
WO-2023221565-A1 METHOD FOR DIFFERENTIATING INDUCED PLURIPOTENT STEM CELL INTO PANCREATIC ISLET AND USE THEREOF IN TREATING TYPE I DIABETES MELLITUS 呈诺再生医学科技(北京)有限公司 2023-11-23 WO claimed
CN-115838684-B In-vitro accurate simulation method for pulmonary fibrosis 淇嘉科技(天津)有限公司 2023-05-12 CN claimed
CN-115786245-A Method for constructing human bionic lung organoid 淇嘉科技(天津)有限公司 2023-03-14 CN claimed
CN-114836369-A Method for differentiating induced pluripotent stem cells into pancreatic islets and application of induced pluripotent stem cells in treatment of type I diabetes 呈诺再生医学科技(北京)有限公司 2022-08-02 CN claimed
CN-114807015-A Induction method for promoting islet alpha cells to be converted into beta cells and application thereof 呈诺再生医学科技(北京)有限公司 2022-07-29 CN claimed
CN-108721282-B Application of UK383367 in preparation of medicine for relieving renal fibrosis related diseases 南京市儿童医院 2022-02-15 CN claimed
EP-1240152-B1 OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LTD (GB) 2004-12-08 EP claimed
US-20030119807-A1 3-Heterocyclylpropanohydroxamic acids BAILEY SIMON (US) 2003-06-26 US claimed
JP-2003519133-A 2003-06-17 JP claimed
CN-1423638-A Oxazolyl hydroxamic acids as procollagen C-protease inhibitors PFIZER LTD (US) 2003-06-11 CN claimed
EP-1240152-A1 OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS Pfizer Limited (GB) 2002-09-18 EP claimed
US-6448278-B2 ANTISCARRING AGENT PFIZER INC. 2002-09-10 US claimed
US-20010021718-A1 Procollagen C-proteinase inhibitors PFIZER INC. 2001-09-13 US claimed
WO-2001047901-A1 OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LIMITED (GB) 2001-07-05 WO claimed
US-20250382580-A1 COMPOSITIONS AND METHODS FOR ACCELERATED PRODUCTION OF THYMIC CELLS FROM PLURIPOTENT STEM CELLS UNIV COLORADO REGENTS (US) 2025-12-18 US disclosed
EP-4608977-A1 COMPOSITIONS AND METHODS FOR ACCELERATED PRODUCTION OF THYMIC CELLS FROM PLURIPOTENT STEM CELLS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2025-09-03 EP disclosed
CN-120082503-A Liver progenitor organoid culture medium and culture method 成都艾名迈德医学检验实验室有限公司 2025-06-03 CN disclosed
WO-2025059227-A1 COMPOSITIONS AND METHODS FOR GENERATING AND USING PATIENT-SPECIFIC THYMUS-BEARING MICE THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2025-03-20 WO disclosed
CN-119162082-A Method for preparing extrahepatic vesicles/apoptotic vesicles by inducing fibroblasts to be directly reprogrammed into liver-like cells and application of method 中国人民解放军海军军医大学 2024-12-20 CN disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO disclosed
CN-118308295-B Additive, culture medium and method for promoting cell to produce collagen 上海遇见味来生物技术有限公司 2024-08-27 CN disclosed
CN-118308295-A Additive, culture medium and method for promoting cell to produce collagen 上海遇见味来生物技术有限公司 2024-07-09 CN disclosed
WO-2024091485-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING PULMONARY FIBROSIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-05-02 WO disclosed
WO-2024091676-A1 COMPOSITIONS AND METHODS FOR ACCELERATED PRODUCTION OF THYMIC CELLS FROM PLURIPOTENT STEM CELLS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2024-05-02 WO disclosed
EP-2968536-B1 METHODS FOR MODULATING CHEMOTHERAPEUTIC CYTOTOXICITY US HEALTH (US) 2023-06-28 EP disclosed
CN-115786245-B Human bionic lung organoid construction method 淇嘉科技(天津)有限公司 2023-05-12 CN disclosed
CN-115838684-B In-vitro accurate simulation method for pulmonary fibrosis 淇嘉科技(天津)有限公司 2023-05-12 CN disclosed
CN-115786244-B Screening process of anti-pulmonary fibrosis drug effect 淇嘉科技(天津)有限公司 2023-05-02 CN disclosed
CN-115772492-B Method for constructing pulmonary fibrosis disease model in vitro by using bleomycin 淇嘉科技(天津)有限公司 2023-05-02 CN disclosed
CN-115838684-A In-vitro accurate simulation method for pulmonary fibrosis 淇嘉科技(天津)有限公司 2023-03-24 CN disclosed
CN-115786245-A Method for constructing human bionic lung organoid 淇嘉科技(天津)有限公司 2023-03-14 CN disclosed
CN-115786244-A Anti-pulmonary fibrosis drug effect screening process 淇嘉科技(天津)有限公司 2023-03-14 CN disclosed
CN-115772492-A Method for constructing pulmonary fibrosis disease model in vitro by using bleomycin 淇嘉科技(天津)有限公司 2023-03-10 CN disclosed
CN-114836369-B Method for differentiating induced pluripotent stem cells into pancreatic islets and application of induced pluripotent stem cells in treatment of type I diabetes 呈诺再生医学科技(北京)有限公司 2023-01-17 CN disclosed
CN-114807015-B Induction method for promoting islet alpha cells to be converted into beta cells and application thereof 呈诺再生医学科技(北京)有限公司 2022-11-22 CN disclosed
US-20220244263-A1 METHODS FOR TREATING SMALL CELL NEUROENDOCRINE AND RELATED CANCERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-04 US disclosed
CN-114836369-A Method for differentiating induced pluripotent stem cells into pancreatic islets and application of induced pluripotent stem cells in treatment of type I diabetes 呈诺再生医学科技(北京)有限公司 2022-08-02 CN disclosed
CN-114807015-A Induction method for promoting islet alpha cells to be converted into beta cells and application thereof 呈诺再生医学科技(北京)有限公司 2022-07-29 CN disclosed
US-20220184111-A1 METHODS FOR MODULATING CHEMOTHERAPEUTIC CYTOTOXICITY THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2022-06-16 US disclosed
US-11285169-B2 Methods for modulating chemotherapeutic cytotoxicity THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-03-29 US disclosed
CN-108721282-B Application of UK383367 in preparation of medicine for relieving renal fibrosis related diseases 南京市儿童医院 2022-02-15 CN disclosed
CN-108721282-B Application of UK383367 in preparation of medicine for relieving renal fibrosis related diseases 南京市儿童医院 2022-02-15 CN disclosed
CN-108721282-B Application of UK383367 in preparation of medicine for relieving renal fibrosis related diseases 南京市儿童医院 2022-02-15 CN disclosed
US-6897306-B2 3-heterocyclylpropanohydroxamic acids PFIZER PRODUCTS, INC. (US) 2005-05-24 US disclosed
EP-1240152-B1 OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LTD (GB) 2004-12-08 EP disclosed
US-20030119807-A1 3-Heterocyclylpropanohydroxamic acids BAILEY SIMON (US) 2003-06-26 US disclosed
CN-1423638-A Oxazolyl hydroxamic acids as procollagen C-protease inhibitors PFIZER LTD (US) 2003-06-11 CN disclosed
EP-1240152-A1 OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS Pfizer Limited (GB) 2002-09-18 EP disclosed
US-6448278-B2 ANTISCARRING AGENT PFIZER INC. 2002-09-10 US disclosed
US-20010021718-A1 Procollagen C-proteinase inhibitors PFIZER INC. 2001-09-13 US disclosed
WO-2001047901-A1 OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LIMITED (GB) 2001-07-05 WO disclosed
WO-2001047901-A1 OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LIMITED (GB) 2001-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010021718-A1 Procollagen C-proteinase inhibitors MMP1, CTSL, PREP BMP1 166/4885PDE4A 2310/4885PDE4B 3399/4885
US-20030119807-A1 3-Heterocyclylpropanohydroxamic acids CPA1, MMP1, PREP BMP1 79/4885PDE4A 1831/4885PDE4B 2192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.