Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25191915 | 0.84 | PTGS1 (0.53) | FFAR1FFAR4LTA4HEPHX2BCHE | |
| Phenethyl Isocyanate SCHEMBL5918 | 0.83 | MIF (0.63) | LMNASLC6A2SLC6A3HIF1A | |
| SCHEMBL15729871 | 0.79 | NQO1 (0.48) | CA12CA1CA2CA9LMNA | |
| SCHEMBL13097950 | 0.78 | FFAR1 (0.50) | FFAR1FFAR4LTA4HEPHX2MMP12 | |
| SCHEMBL2587464 | 0.78 | LTA4H (0.57) | FFAR1FFAR4LTA4HEPHX2BCHE | |
| SCHEMBL331135 | 0.77 | MIF (0.48) | CA12CA1CA2CA9HIF1A | |
| SCHEMBL11783167 | 0.76 | KDM4E (0.56) | BCHELMNACYP1A2HDAC6 | |
| SCHEMBL4598946 | 0.76 | TRPA1 (0.50) | FFAR1MMP12CA12CA1CA2 | |
| SCHEMBL993322 | 0.76 | LMNA (0.46) | LMNACYP1A2HIF1AHDAC6L3MBTL1 | |
| SCHEMBL5543890 | 0.76 | FFAR1 (0.58) | FFAR1FFAR4LTA4HEPHX2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345954-B1 | POLYROTAXANE, PRODUCTION METHOD THEREFOR, AND OPTICAL COMPOSITION CONTAINING SAID POLYROTAXANE | TOKUYAMA CORP (JP) | 2023-07-05 | — | — | EP | disclosed |
| US-11578174-B2 | Polyrotaxane, production method therefor, and optical composition containing said polyrotaxane | TOKUYAMA CORPORATION (JP) | 2023-02-14 | — | — | US | disclosed |
| CN-111154056-B | Optical composition containing polyrotaxane | 株式会社德山 | 2021-12-21 | — | — | CN | disclosed |
| CN-107922605-B | Polyrotaxane, process for producing the same, and optical composition containing the same | 株式会社德山 | 2020-12-11 | — | — | CN | disclosed |
| CN-111154056-A | Optical composition containing polyrotaxane | 株式会社德山 | 2020-05-15 | — | — | CN | disclosed |
| US-20200071467-A1 | Polyrotaxane, Production Method Therefor, and Optical Composition Containing said Polyrotaxane | TOKUYAMA CORPORATION (JP) | 2020-03-05 | — | — | US | disclosed |
| US-20180312643-A1 | Polyrotaxane, Production Method Therefor, and Optical Composition Containing said Polyrotaxane | TOKUYAMA CORPORATION (JP) | 2018-11-01 | — | — | US | disclosed |
| EP-3345954-A1 | POLYROTAXANE, PRODUCTION METHOD THEREFOR, AND OPTICAL COMPOSITION CONTAINING SAID POLYROTAXANE | Tokuyama Corporation (JP) | 2018-07-11 | — | — | EP | disclosed |
| EP-0927049-B1 | LABELLED ELASTASE INHIBITORS | AMERSHAM PLC (GB) | 2005-05-11 | — | — | EP | disclosed |
| US-6375926-B1 | HUMAN LEUCOCYTE ELASTASE (HLE) INHIBITOR LABELLED WITH A DETECTABLE MOIETY WHERE THE INHIBITOR IS SYNTHETIC AND THE DETECTABLE MOIETY IS CHOSEN FROM A RADIOACTIVE ISOTOPE, A PARAMAGNETIC ION, A RADIOPAQUE COMPOUND AND AN ULTRASOUND | AMERSHAM INTERNATIONAL PLC | 2002-04-23 | — | — | US | disclosed |
| EP-0927049-A2 | LABELLED ELASTASE INHIBITORS | AMERSHAM INTERNATIONAL plc (GB) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998010800-A2 | LABELLED ELASTASE INHIBITORS | AMERSHAM INTERNATIONAL PLC (GB) | 1998-03-19 | — | — | WO | disclosed |