Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | RNF4 | P78317 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184671 | 0.89 | HDAC1 (0.58) | HDAC1MEN1KMT2APGRRAB9A | |
| SCHEMBL675578 | 0.87 | KMT2A (0.76) | HDAC1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL18657627 | 0.86 | RAB9A (0.74) | HDAC1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL9370053 | 0.86 | EPHX2 (0.71) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5197660 | 0.85 | MEN1 (0.72) | HDAC1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL12167954 | 0.84 | RAB9A (0.77) | HDAC1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL5183704 | 0.84 | ALDH1A1 (0.75) | HDAC1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL5183360 | 0.82 | MEN1 (0.54) | HDAC1MEN1KMT2APGRRAB9A | |
| SCHEMBL5184646 | 0.82 | NPC1 (0.69) | HDAC1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL13188232 | 0.81 | HDAC8 (0.71) | HDAC1PGRSMN1; SMN2HPGDHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581484-A1 | HYDROXAMIC ACID DERIVATIVES HAVING ANTI-INFLAMMATORY ACTION | ITALFARMACO S.p.A. (IT) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004063146-A1 | HYDROXAMIC ACID DERIVATIVES HAVING ANTI-INFLAMMATORY ACTION | ITALFARMACO SPA (IT) | 2004-07-29 | — | — | WO | disclosed |