Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.71 |
| ▸ | MMP1 | P03956 | 2/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.66 |
| ▸ | CA1 | P00915 | 3/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.65 |
| ▸ | IDO1 | P14902 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.65 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671653 | 0.83 | HDAC8 (1.00) | HDAC8HDAC1HDAC6CA1HDAC2 | |
| SCHEMBL6252549 | 0.82 | HPGD (0.85) | MMP1HDAC3PGRPARP10HPGD | |
| SCHEMBL21628916 | 0.82 | HDAC6 (0.77) | HDAC8HDAC1HDAC6CA1HDAC2 | |
| SCHEMBL13485809 | 0.82 | CA1 (0.58) | HDAC8MMP1HDAC1HDAC6CA1 | |
| SCHEMBL2835202 | 0.82 | ALDH1A1 (0.65) | MMP1CA1CA12CA9HDAC3 | |
| SCHEMBL6430869 | 0.81 | HDAC1 (0.62) | HDAC8MMP1HDAC1HDAC6HDAC2 | |
| SCHEMBL19619022 | 0.81 | PGR (0.86) | HDAC8HDAC1HDAC6HDAC2PGR | |
| SCHEMBL22192258 | 0.81 | PGR (0.93) | HDAC1PGRHPGDHTTSMN1; SMN2 | |
| SCHEMBL5636163 | 0.81 | LTA4H (0.67) | MMP1CA1CA12CA9HDAC3 | |
| Benzohydroxamate SCHEMBL133061 | 0.80 | HDAC8 (1.00) | HDAC8HDAC1HDAC6CA1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |