Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11922686 | 0.89 | SIGMAR1 (0.49) | SIGMAR1KDM4ESMN1; SMN2LOXL2CYP1A2 | |
| SCHEMBL4001727 | 0.86 | KDM4E (0.47) | KDM4ESMN1; SMN2LOXL2CYP1A2CYP3A4 | |
| SCHEMBL15308555 | 0.82 | KDM4E (0.51) | SIGMAR1KDM4ESMN1; SMN2LOXL2CYP1A2 | |
| SCHEMBL8828685 | 0.79 | HRH1 (0.56) | SIGMAR1KDM4ESMN1; SMN2LOXL2CYP1A2 | |
| SCHEMBL10926250 | 0.79 | SIGMAR1 (0.47) | SIGMAR1KDM4ESMN1; SMN2LOXL2CYP1A2 | |
| SCHEMBL11922700 | 0.79 | SIGMAR1 (0.72) | SIGMAR1 | |
| SCHEMBL210990 | 0.79 | TAAR1 (0.60) | KDM4ESMN1; SMN2LOXL2CYP1A2CYP3A4 | |
| Trimethylammonium SCHEMBL9242104 | 0.79 | ALDH1A1 (0.50) | SMN1; SMN2LOXL2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13123538 | 0.78 | KDM4E (0.42) | SIGMAR1KDM4ESMN1; SMN2LOXL2CYP1A2 | |
| SCHEMBL18137939 | 0.78 | KCNH2 (0.61) | SIGMAR1CYP1A2CYP3A4CYP2D6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615925-B1 | IMIDAZOPYRIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS | IPSEN PHARMA (FR) | 2009-05-27 | — | — | EP | disclosed |
| EP-1606288-A1 | BENZENESULPHONAMIDE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF FOR TREATMENT OF PAIN | LABORATOIRES FOURNIER S.A. (FR) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004087700-A1 | BENZENESULPHONAMIDE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF FOR TREATMENT OF PAIN | LABORATOIRES FOURNIER S.A. (FR) | 2004-10-14 | — | — | WO | disclosed |