Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092468 | 0.86 | SIGMAR1 (0.53) | TAAR1HRH3CHRNA7LOXL2CHRM5 | |
| SCHEMBL28753740 | 0.85 | SIGMAR1 (0.62) | TAAR1HRH3CHRNA7LOXL2HRH1 | |
| SCHEMBL18762839 | 0.82 | HRH3 (0.84) | TAAR1HRH3CHRNA7CYP1A2CYP2C19 | |
| SCHEMBL4001727 | 0.80 | KDM4E (0.47) | CHRNA7LOXL2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3995171 | 0.79 | SIGMAR1 (0.46) | CHRNA7LOXL2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6430952 | 0.79 | SIGMAR1 (0.49) | HRH3CHRNA7LOXL2CYP1A2CYP3A4 | |
| SCHEMBL17886874 | 0.79 | LOXL2 (0.43) | TAAR1HRH3CHRNA7LOXL2CYP1A2 | |
| SCHEMBL3031908 | 0.77 | LOXL2 (0.46) | HRH3LOXL2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6826869 | 0.77 | CYP1A2 (0.42) | TAAR1HRH3CHRNA7LOXL2CYP1A2 | |
| SCHEMBL4447413 | 0.77 | CYP1A2 (0.42) | TAAR1HRH3CHRNA7LOXL2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118834490-A | Photo-crosslinkable perfluorinated ion membrane and preparation method thereof | 上海交通大学 | 2024-10-25 | — | — | CN | claimed |
| US-4402843-A | Viscosity index improvers with dispersant properties prepared by reaction of lithiated hydrogenated copolymers with 4-substituted aminopyridines | PHILLIPS PETROLEUM COMPANY (US) | 1983-09-06 | — | — | US | claimed |
| CN-118834490-A | Photo-crosslinkable perfluorinated ion membrane and preparation method thereof | 上海交通大学 | 2024-10-25 | — | — | CN | disclosed |
| WO-2022112352-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |
| US-20170226132-A1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2017-08-10 | — | — | US | disclosed |
| EP-2476682-B1 | 8-OXODIHYDROPURINE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO LTD (JP) | 2017-04-26 | — | — | EP | disclosed |
| US-20160185780-A1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2016-06-30 | — | — | US | disclosed |
| US-20160151335-A1 | METHODS OF MODULATING CFTR ACTIVITY | PROTEOSTASIS THERAPEUTICS, INC. (US) | 2016-06-02 | — | — | US | disclosed |
| US-9193752-B2 | 5′-substituted bicyclic nucleosides and oligomeric compounds prepared therefrom | ISIS PHARMACEUTICALS, INC. (US) | 2015-11-24 | — | — | US | disclosed |
| WO-2014210159-A1 | METHODS OF MODULATING CFTR ACTIVITY | PROTEOSTASIS THERAPEUTICS, INC. (US) | 2014-12-31 | — | — | WO | disclosed |
| EP-2314594-B1 | 6-modified bicyclic nucleic acid analogs | ISIS PHARMACEUTICALS INC (US) | 2014-07-23 | — | — | EP | disclosed |
| US-20060178360-A1 | Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain | LABORATOIRES FOURNIER S.A. (FR) | 2006-08-10 | — | — | US | disclosed |
| CN-1764661-A | Benzenesulfonamide derivatives, process for their preparation and their use for the treatment of pain | FOURNIER LAB SA (FR) | 2006-04-26 | — | — | CN | disclosed |
| EP-1606288-A1 | BENZENESULPHONAMIDE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF FOR TREATMENT OF PAIN | LABORATOIRES FOURNIER S.A. (FR) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004087700-A1 | BENZENESULPHONAMIDE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF FOR TREATMENT OF PAIN | LABORATOIRES FOURNIER S.A. (FR) | 2004-10-14 | — | — | WO | disclosed |
| US-20040009938-A1 | Methods of enhancing renal uptake of oligonucleotides | ISIS PHARMACEUTICAL INC. | 2004-01-15 | — | — | US | disclosed |
| US-6673912-B1 | 2′-O-aminoethyloxyethyl-modified oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2004-01-06 | — | — | US | disclosed |
| US-6600032-B1 | Compound for use in the treatment of viral, protozoan and parasitic infections | ISIS PHARMACEUTICALS, INC. | 2003-07-29 | — | — | US | disclosed |
| US-4546176-A | 7-Carboxymethoxyphenylacetamido-3-cephem derivatives and antibacterial preparations containing the same | EISAI CO., LTD. (JP) | 1985-10-08 | — | — | US | disclosed |
| US-4402843-A | Viscosity index improvers with dispersant properties prepared by reaction of lithiated hydrogenated copolymers with 4-substituted aminopyridines | PHILLIPS PETROLEUM COMPANY (US) | 1983-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185780-A1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | ABL1, JAK2, JAK1 | TAAR1 1344/4885HRH3 1610/4885CHRNA7 2234/4885 |
| US-20060178360-A1 | Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain | LTB4R2, BDKRB2, TBXA2R | TAAR1 2722/4885HRH3 863/4885CHRNA7 1687/4885 |
| US-20160151335-A1 | METHODS OF MODULATING CFTR ACTIVITY | CFTR, HSP90B1, SERPINB1 | TAAR1 4242/4885HRH3 3764/4885CHRNA7 2885/4885 |
| US-20170226132-A1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | ABL1, JAK2, JAK1 | TAAR1 1344/4885HRH3 1610/4885CHRNA7 2234/4885 |
| US-20040009938-A1 | Methods of enhancing renal uptake of oligonucleotides | NUDT1, SLC29A2, DUT | TAAR1 4217/4885HRH3 1143/4885CHRNA7 2498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.