Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15338801 | 0.88 | KMT2A (0.60) | KMT2ATLR8CYP19A1TSHRMAPT | |
| SCHEMBL24168945 | 0.84 | KEAP1 (0.57) | KMT2ATLR8CYP19A1TSHRMAPT | |
| SCHEMBL27774356 | 0.82 | CYP19A1 (0.54) | KMT2ACYP19A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL17261567 | 0.81 | KMT2A (0.52) | KMT2ATLR8MAPTSMN1; SMN2PDE10A | |
| SCHEMBL14387688 | 0.81 | KMT2A (0.51) | KMT2ACYP19A1MAPTSMN1; SMN2PDE10A | |
| SCHEMBL11123118 | 0.80 | KMT2A (0.59) | KMT2ACYP19A1TP53MAPTSMN1; SMN2 | |
| SCHEMBL26219682 | 0.80 | CYP19A1 (0.44) | KMT2ATLR8CYP19A1 | |
| SCHEMBL27774531 | 0.79 | LTA4H (0.41) | KMT2ATLR8CYP19A1TSHRNR1H3 | |
| SCHEMBL28782368 | 0.79 | KEAP1 (0.59) | KMT2ATLR8CYP19A1TSHRMAPT | |
| SCHEMBL11679229 | 0.79 | CYP19A1 (0.49) | KMT2ATLR8CYP19A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694123-B1 | TOPICAL FORMULATIONS COMPRISING A 1-N-ARYLPYRAZOLE DERIVATIVE AND A FORMAMIDINE | MERIAL INC (US) | 2017-09-06 | — | — | EP | claimed |
| US-20050137244-A1 | Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz | MERIAL, INC. | 2005-06-23 | — | — | US | claimed |
| CN-116490201-A | Inhibitors of YAP/TAZ-TEAD tumor proteins, their synthesis and use | 布里奇恩生物科学公司 | 2023-07-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137244-A1 | Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz | MGAT2, MGAT1, MIF | KMT2A 2162/4885TLR8 4361/4885CYP19A1 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.