Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.41 |
| ▸ | MMP2 | P08253 | 4/20 | 0.41 |
| ▸ | MMP9 | P14780 | 4/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431413 | 1.00 | MMP1 (0.41) | MMP1MMP2MMP9EGFRMAOB | |
| SCHEMBL6431411 | 0.93 | MMP1 (0.41) | MMP1MMP2MMP9EGFRMAOB | |
| SCHEMBL4834668 | 0.81 | MMP1 (0.41) | MMP1MMP2MMP9EGFRMAOB | |
| SCHEMBL4834693 | 0.81 | MMP1 (0.41) | MMP1MMP2MMP9EGFRMAOB | |
| SCHEMBL4834188 | 0.80 | RAB9A (0.41) | MMP1MMP2MMP9EGFRMAOB | |
| SCHEMBL6429681 | 0.79 | CYP11B1 (0.41) | MEN1ALDH1A1MAPTKMT2ARAB9A | |
| SCHEMBL4833451 | 0.79 | BTK (0.42) | MMP1MMP2MMP9EGFRMAOB | |
| SCHEMBL27632195 | 0.78 | MAOB (0.47) | MMP1MMP2MMP9EGFRMAOB | |
| SCHEMBL29208306 | 0.76 | CCNC (0.42) | MMP1MMP2MMP9EGFRNPC1 | |
| SCHEMBL6434504 | 0.76 | CCNC (0.42) | MMP1MMP2MMP9EGFRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556032-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | Takeda Pharmaceutical Company Limited (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039365-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-13 | — | — | WO | disclosed |