Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429685 | 0.93 | CYP11B1 (0.42) | CYP11B1CYP11B2ALDH1A1MCHR1GAA | |
| SCHEMBL6432385 | 0.83 | RAB9A (0.40) | ALDH1A1MCHR1GAALMNARXFP1 | |
| SCHEMBL4833854 | 0.81 | ENPP2 (0.45) | CYP11B1CYP11B2ALDH1A1MCHR1GAA | |
| SCHEMBL4836713 | 0.80 | CYP11B1 (0.48) | CYP11B1CYP11B2ALDH1A1MCHR1GAA | |
| SCHEMBL6431408 | 0.79 | MMP1 (0.41) | ALDH1A1LMNARXFP1TP53RAB9A | |
| SCHEMBL6431413 | 0.79 | MMP1 (0.41) | ALDH1A1LMNARXFP1TP53RAB9A | |
| SCHEMBL4837021 | 0.79 | CYP11B1 (0.44) | CYP11B1CYP11B2ALDH1A1MCHR1GAA | |
| SCHEMBL27632133 | 0.78 | RAB9A (0.40) | CYP11B1CYP11B2ALDH1A1GAALMNA | |
| SCHEMBL6432392 | 0.76 | RAB9A (0.40) | ALDH1A1MCHR1GAALMNARXFP1 | |
| SCHEMBL4837015 | 0.76 | LMNA (0.39) | CYP11B1CYP11B2ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556032-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | Takeda Pharmaceutical Company Limited (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039365-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-13 | — | — | WO | disclosed |