Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.68 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | IDH1 | O75874 | 5/20 | 0.59 |
| ▸ | PTGES | O14684 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | IDH2 | P48735 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14113154 | 0.84 | P2RX1 (0.66) | NTRK1CDK19MEN1KMT2AGRIK1 | |
| SCHEMBL14459439 | 0.82 | KDR (0.76) | NTRK1CDK19MEN1KMT2AGRIK1 | |
| SCHEMBL5597796 | 0.82 | NTRK1 (0.79) | NTRK1CDK19MEN1KMT2AGRIK1 | |
| SCHEMBL3966450 | 0.82 | NTRK1 (0.71) | NTRK1CDK19MEN1KMT2AGRIK1 | |
| SCHEMBL1463419 | 0.81 | NTRK1 (0.81) | NTRK1CDK19MEN1KMT2AGRIK1 | |
| SCHEMBL1463468 | 0.81 | NTRK1 (1.00) | NTRK1CDK19MEN1KMT2AGRIK1 | |
| SCHEMBL29763181 | 0.81 | NTRK1 (1.00) | NTRK1CDK19MEN1KMT2AGRIK1 | |
| SCHEMBL1462338 | 0.81 | NTRK1 (0.73) | NTRK1CDK19MEN1KMT2AGRIK1 | |
| SCHEMBL1463283 | 0.80 | NTRK1 (0.76) | NTRK1CDK19MEN1KMT2AGRIK1 | |
| SCHEMBL8372525 | 0.80 | NTRK1 (0.71) | NTRK1CDK19MEN1KMT2AGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080112-A1 | Compounds for use in disorders associated with mast cell or basophil acitvity | POSEIDON PHARMACEUTICALS A/S (DK) | 2005-04-14 | — | — | US | claimed |
| US-20050080112-A1 | Compounds for use in disorders associated with mast cell or basophil acitvity | POSEIDON PHARMACEUTICALS A/S (DK) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080112-A1 | Compounds for use in disorders associated with mast cell or basophil acitvity | CPA3, HNMT, CMA1 | NTRK1 2665/4885CDK19 3829/4885MEN1 903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.