Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 8/20 | 0.57 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433663 | 0.88 | F10 (0.50) | CCR2PPIAMRGPRX4F10FFAR1 | |
| SCHEMBL6433546 | 0.87 | CCR2 (0.67) | CCR2F10FEN1 | |
| SCHEMBL6432935 | 0.82 | CCR2 (0.64) | CCR2F10FEN1 | |
| SCHEMBL6433702 | 0.82 | F10 (0.54) | F10 | |
| SCHEMBL6432960 | 0.81 | CCR2 (0.65) | CCR2F10FEN1 | |
| SCHEMBL6432749 | 0.81 | CCR2 (0.62) | CCR2FEN1 | |
| SCHEMBL6432803 | 0.80 | CCR2 (0.70) | CCR2F10FFAR1FFAR4SRD5A2 | |
| SCHEMBL6433076 | 0.80 | CCR2 (0.77) | CCR2F10FEN1 | |
| SCHEMBL6433700 | 0.78 | CCR2 (0.54) | CCR2F10 | |
| SCHEMBL6594219 | 0.77 | CCR2 (0.57) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |