Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 7/20 | 0.70 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | F10 | P00742 | 3/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.55 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420738 | 0.90 | F10 (0.70) | CCR2SRD5A2F10LTB4RLTB4R2 | |
| SCHEMBL6432419 | 0.89 | F10 (0.71) | CCR2SRD5A2F10PPARGCNR1 | |
| SCHEMBL6439399 | 0.89 | F10 (0.60) | CCR2SRD5A2F10LTB4RLTB4R2 | |
| SCHEMBL6433076 | 0.84 | CCR2 (0.77) | CCR2F10GPR35 | |
| SCHEMBL3967516 | 0.83 | CCR2 (0.73) | CCR2SRD5A2F10LTB4RLTB4R2 | |
| SCHEMBL6436016 | 0.83 | CCR2 (1.00) | CCR2GPR35 | |
| SCHEMBL6436704 | 0.82 | CCR2 (0.78) | CCR2F10GPR35 | |
| SCHEMBL6433082 | 0.82 | CCR2 (0.78) | CCR2F10GPR35 | |
| SCHEMBL6432426 | 0.82 | CCR2 (0.78) | CCR2F10NTRK1GPR35CNR1 | |
| SCHEMBL6432795 | 0.81 | F10 (0.68) | CCR2SRD5A2F10LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |