Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2101945 | 0.90 | ALDH1A1 (0.33) | ALDH1A1CYP3A4ELANEPSMB5TYMP | |
| SCHEMBL2270492 | 0.86 | ALDH1A1 (0.34) | ALDH1A1CYP3A4ELANEPSMB5TDP1 | |
| SCHEMBL2101831 | 0.86 | TYMP (0.32) | ALDH1A1CYP3A4ELANETYMPTDP1 | |
| SCHEMBL1584751 | 0.81 | NPC1 (0.33) | ALDH1A1CYP3A4ELANEPSMB5 | |
| SCHEMBL1258428 | 0.81 | NPC1 (0.33) | ALDH1A1CYP3A4ELANEPSMB5 | |
| SCHEMBL27912770 | 0.80 | ALDH1A1 (0.41) | ALDH1A1CYP3A4ELANEPSMB5TYMP | |
| SCHEMBL1585575 | 0.77 | JAK2 (0.31) | — | |
| SCHEMBL2275575 | 0.77 | PSMB5 (0.32) | PSMB5 | |
| SCHEMBL8776583 | 0.77 | PSMB5 (0.32) | PSMB5 | |
| SCHEMBL3166128 | 0.75 | JAK2 (0.33) | PSMB5CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1241190-B1 | Rubber composite | GOODYEAR TIRE & RUBBER (US) | 2005-01-26 | — | — | EP | claimed |