Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6432930 | 1.00 | CA1 (0.38) | CA1APPHPGDCYP2C19SMN1; SMN2 | |
| SCHEMBL272363 | 0.83 | ESR1 (0.38) | HPGDESR1 | |
| SCHEMBL30423535 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TP53TDP1TRPA1 | |
| SCHEMBL8733104 | 0.78 | NR1H2 (0.39) | APPHPGDCYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL6434758 | 0.78 | APP (0.39) | CA1APPHPGDCYP2C19SMN1; SMN2 | |
| SCHEMBL6434753 | 0.78 | APP (0.39) | CA1APPHPGDCYP2C19SMN1; SMN2 | |
| SCHEMBL8733107 | 0.78 | NR1H2 (0.39) | APPHPGDCYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL27043327 | 0.75 | APP (0.54) | APPMEN1MAPTKMT2ANPC1 | |
| SCHEMBL6433024 | 0.75 | ESR1 (0.35) | HPGDESR1 | |
| SCHEMBL15445504 | 0.72 | ACHE (0.47) | CA1HPGDSMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276807-B1 | CURABLE SILICONE RESIN COMPOSITION AND REACTIVE SILICON COMPOUNDS | DOW CORNING (US) | 2005-10-12 | — | — | EP | disclosed |
| US-6780471-B2 | USING CROSSLINKER WITH NONFLEXIBLE LINKAGE INCLUDING AT LEAST ONE P-ARYLENE MOIETY FOR SPATIAL SEPARATION; FLEXURAL STRENGTH, FRACTURE TOUGHNESS, MODULUS AND/OR MECHANICAL DAMPING | DOW CORNING CORPORATION | 2004-08-24 | — | — | US | disclosed |
| US-20030130389-A1 | Curable silicone resin composition and reactive silicon compounds | DOW CORNING LIMITED (GB) | 2003-07-10 | — | — | US | disclosed |