Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.63 |
| ▸ | CCR2 | P41597 | 9/20 | 0.63 |
| ▸ | F2 | P00734 | 3/20 | 0.60 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.57 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27497454 | 0.87 | PLA2G10 (0.74) | F10CCR2F2PLA2G10GPR35 | |
| SCHEMBL15712747 | 0.84 | CCR2 (0.74) | F10CCR2GPR35 | |
| SCHEMBL6432795 | 0.83 | F10 (0.68) | F10CCR2F2PLA2G10 | |
| Trifluoroacetic Acid SCHEMBL6436682 | 0.83 | F10 (0.84) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL6432601 | 0.81 | F10 (0.77) | F10F2 | |
| SCHEMBL6433082 | 0.80 | CCR2 (0.78) | F10CCR2F2PLA2G10GPR35 | |
| SCHEMBL3963187 | 0.78 | PLA2G10 (0.83) | F10CCR2F2PLA2G10GPR35 | |
| SCHEMBL6433920 | 0.78 | F10 (0.67) | F10F2 | |
| SCHEMBL27718927 | 0.77 | CCR2 (0.58) | F10CCR2F2 | |
| SCHEMBL6433216 | 0.76 | F10 (0.78) | F10CCR2F2PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |