Trifluoroacetic Acid

SCHEMBL6436682

NC(=S)c1cccc(CNC(=O)c2cc3cc(N)ccc3n2Cc2cccc(C(N)=S)c2)c1.O=C(O)C(F)(F)F

nearest known ligand 0.84

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	20/20	0.84

▸	F2	P00734	6/20	0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Trifluoroacetic Acid SCHEMBL6432601	0.96	F10 (0.77)	F10F2
Trifluoroacetic Acid SCHEMBL6437256	0.91	F10 (1.00)	F10F2
Trifluoroacetic Acid SCHEMBL6439393	0.87	F10 (0.92)	F10F2
Trifluoroacetic Acid SCHEMBL6433228	0.84	F10 (0.72)	F10F2
SCHEMBL6433052	0.83	F10 (0.63)	F10F2
Trifluoroacetic Acid SCHEMBL6433532	0.81	F10 (0.96)	F10F2
Trifluoroacetic Acid SCHEMBL6432430	0.80	F10 (0.96)	F10F2
SCHEMBL6432399	0.80	F10 (0.84)	F10F2
Trifluoroacetic Acid SCHEMBL6436624	0.80	F10 (0.67)	F10F2
SCHEMBL6437209	0.79	F10 (0.59)	F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1042287-B1	INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA	AVENTIS PHARMA GMBH (DE)	2005-04-20	—	—	EP	disclosed
US-6337344-B1	ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS	AVENTIS PHARMA DEUTSCHLAND GMBH (DE)	2002-01-08	—	—	US	disclosed
EP-1042287-A1	INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA	Aventis Pharma Deutschland GmbH (DE)	2000-10-11	—	—	EP	disclosed
WO-1999033800-A1	INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA	AVENTIS PHARMA DEUTSCHLAND GMBH (DE)	1999-07-08	—	—	WO	disclosed