Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3177458 | 0.89 | CYP3A4 (0.50) | CYP3A4TSHRCYP1A2TRPA1TDP1 | |
| SCHEMBL305469 | 0.89 | CYP3A4 (0.50) | CYP3A4TSHRCYP1A2TRPA1TDP1 | |
| SCHEMBL305480 | 0.89 | CYP3A4 (0.50) | CYP3A4TSHRCYP1A2TRPA1TDP1 | |
| Ethane SCHEMBL20537385 | 0.85 | CYP3A4 (0.91) | CYP3A4TSHRCYP1A2TRPA1TDP1 | |
| SCHEMBL1396496 | 0.84 | CYP3A4 (1.00) | CYP3A4TSHRCYP1A2TRPA1TDP1 | |
| SCHEMBL12852256 | 0.84 | CYP3A4 (1.00) | CYP3A4TSHRCYP1A2TRPA1TDP1 | |
| SCHEMBL19943 | 0.84 | CYP3A4 (1.00) | CYP3A4TSHRCYP1A2TRPA1TDP1 | |
| SCHEMBL2044965 | 0.84 | CYP3A4 (1.00) | CYP3A4TSHRCYP1A2TRPA1TDP1 | |
| SCHEMBL22966434 | 0.83 | CYP3A4 (0.45) | CYP3A4TSHRCYP1A2TRPA1TDP1 | |
| SCHEMBL22966365 | 0.83 | CYP3A4 (0.45) | CYP3A4TSHRCYP1A2TRPA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572453-A2 | LAYERED ARTICLES HAVING POLYOXYMETHYLENE BLEND SUBSTRATES WITH ENHANCED SURFACE PROPERTIES AND AT LEAST ONE LAYER THEREON AND PROCESS FOR MAKING THE SAME | E.I. du Pont de Nemours and Company (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004058502-A2 | LAYERED ARTICLES HAVING POLYOXYMETHYLENE BLEND SUBSTRATES WITH ENHANCED SURFACE PROPERTIES AND AT LEAST ONE LAYER THEREON AND PROCESS FOR MAKING THE SAME | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-07-15 | — | — | WO | disclosed |
| US-20040121175-A1 | Layered articles having polyoxymethylene blend substrates with enhanced surface properties and at least one layer thereon and process for making the same | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-06-24 | — | — | US | disclosed |
| US-20040118509-A1 | Concentrations to improve surface adhesion characteristics of polyacetal-based compositions | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-06-24 | — | — | US | disclosed |
| US-5344882-A | Blend with thermoplastic polyurethane and nylon, polyprolylene or polyalkylene terephthalate for toughness, impact strength and elongation | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-09-06 | — | — | US | disclosed |