SCHEMBL7591144

SCHEMBL7591144

CCC(C)C(O)CC(O)CO

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28946275 0.84 TSHR (0.40) TSHR
SCHEMBL16882890 0.84 TSHR (0.40) TSHR
SCHEMBL13839699 0.84 LMNA (0.42) LMNAALDH1A1TSHRTDP1THRB
Methacrylic Acid SCHEMBL8922843 0.83 TGFBR1 (0.33)
SCHEMBL16074684 0.80 LMNA (0.38) LMNAALDH1A1TSHRTDP1THRB
SCHEMBL15044106 0.79 LMNA (0.42) LMNAALDH1A1TSHRTDP1THRB
SCHEMBL270330 0.78
SCHEMBL13536696 0.78
SCHEMBL6433370 0.78 LMNA (0.38) LMNATSHR
SCHEMBL4890370 0.78 TSHR (0.35) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606730-B2 Coolant composition and concentrated coolant composition TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2026-04-21 US disclosed
US-20250388799-A1 COOLANT COMPOSITION TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2025-12-25 US disclosed
EP-4632032-A1 COOLANT COMPOSITION CCI Corporation (JP) 2025-10-15 EP disclosed
US-20250313741-A1 Coolant Composition CCI CORPORATION (JP) 2025-10-09 US disclosed
US-20230212446-A1 COOLANT COMPOSITION AND CONCENTRATED COOLANT COMPOSITION TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2023-07-06 US disclosed
CN-115843306-A Coolant composition and concentrated coolant composition 丰田自动车株式会社 2023-03-24 CN disclosed
WO-2022034534-A1 COOLANT COMPOSITION AND CONCENTRATED COOLANT COMPOSITION TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2022-02-17 WO disclosed
CN-109072042-B Viscosity modifier 花王株式会社 2021-06-22 CN disclosed
CN-109689834-B Automotive engine coolant composition, automotive engine concentrated coolant composition, and method of operating an internal combustion engine 丰田自动车株式会社 2021-04-16 CN disclosed
US-10968170-B2 Viscometric properties improver KAO CORPORATION (JP) 2021-04-06 US disclosed
EP-2860208-A1 Urethane foam rubber and composition for forming urethane foam rubber YAMAHA CORPORATION (JP) 2015-04-15 EP disclosed
EP-2860371-A1 LIQUID COOLANT COMPOSITION FOR INTERNAL COMBUSTION ENGINES AND OPERATING METHOD FOR INTERNAL COMBUSTION ENGINES TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2015-04-15 EP disclosed
EP-0802455-B1 Use of a photocurable resin composition for the production of a stereolithographed object TEIJIN SEIKI CO LTD (JP) 2002-10-16 EP disclosed
US-6413698-B1 ACRYLATED POLYURETHANE TEIJIN SEIKI CO., LTD. (JP) 2002-07-02 US disclosed
US-20010003031-A1 Photocurable resin composition TEIJIN SEIKI CO., LTD 2001-06-07 US disclosed
US-6203966-B1 FOR FORMING A THREE-DIMENSIONAL OBJECT BY OPTICAL STEREOLITHOGRAPHY TEIJIN SEIKI CO., LTD. (JP) 2001-03-20 US disclosed
US-6200732-B1 A BLENDS COMPRISING AN ACRYLATED POLYURETHANES OR AN URETHANE ACRYLATE OLIGOMER, A RADICAL, POLYMERIZABLE COMPOUND DIFFERENT FROM THE ABOVE URETHANE ACRYLATE AND AN INITIATOR; FORMING STEREOLITHOGRAPHED OBJECTS WITH DIMENSIONAL ACCURACY TEIJIN SEIKEI CO., LTD. (JP) 2001-03-13 US disclosed
EP-0909793-A1 STEREOLITHOGRAPHIC RESIN COMPOSITION TEIJIN SEIKI CO. Ltd. (JP) 1999-04-21 EP disclosed
US-5731388-A ACRYLATED POLYURETHANE TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 1998-03-24 US disclosed
EP-0802455-A1 Photocurable resin composition Teijin Seiki Co., Ltd. (JP) 1997-10-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606730-B2 Coolant composition and concentrated coolant composition ADH1A, TAS1R1, IPMK LMNA 3555/4885ALDH1A1 296/4885TSHR 3428/4885
US-20250388799-A1 COOLANT COMPOSITION SLC8A1, SLC9A2, SLC9A5 LMNA 3792/4885ALDH1A1 4322/4885TSHR 1541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.