Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433472 | 1.00 | ESR2 (0.59) | ESR2LMNANPC1MAPK1MAPT | |
| SCHEMBL19249421 | 0.81 | TYR (0.48) | ESR2MAPTALDH1A1GAAHPGD | |
| SCHEMBL6437628 | 0.81 | TRPA1 (0.53) | ESR2LMNANPC1MAPK1MAPT | |
| SCHEMBL29871375 | 0.77 | ALDH1A1 (0.43) | ESR2MAPTALDH1A1GAAHPGD | |
| SCHEMBL3162433 | 0.77 | ALDH1A1 (0.43) | ESR2MAPTALDH1A1GAAHPGD | |
| Chloromethane SCHEMBL7706796 | 0.77 | TRPA1 (0.49) | ESR2LMNANPC1MAPK1MAPT | |
| SCHEMBL5363819 | 0.77 | TYR (0.39) | LMNANPC1MAPK1MAPTHSD17B10 | |
| SCHEMBL5619500 | 0.77 | TYR (0.36) | ESR2LMNANPC1MAPK1MAPT | |
| SCHEMBL70722 | 0.76 | ALDH1A1 (0.46) | ESR2MAPTALDH1A1TYRHSP90AA1 | |
| SCHEMBL5935862 | 0.76 | ALDH1A1 (0.46) | ESR2MAPTALDH1A1TYRHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000056702-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2000-09-28 | — | — | WO | claimed |
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | disclosed |