Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ENTPD5 | O75356 | 2/20 | 0.37 |
| ▸ | SHBG | P04278 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437628 | 0.96 | TRPA1 (0.53) | TRPA1ESR2CNR1CNR2ENTPD5 | |
| SCHEMBL7706797 | 0.92 | TRPA1 (0.47) | TRPA1ESR2CNR1CNR2ENTPD5 | |
| SCHEMBL6433469 | 0.77 | ESR2 (0.59) | ESR2ENTPD5SHBGNPC1ESR1 | |
| SCHEMBL6433472 | 0.77 | ESR2 (0.59) | ESR2ENTPD5SHBGNPC1ESR1 | |
| SCHEMBL6433935 | 0.77 | OPRK1 (0.35) | ESR2ENTPD5SHBGESR1OPRK1 | |
| SCHEMBL6436247 | 0.76 | ESR2 (0.45) | ESR2ENTPD5SHBGNPC1ESR1 | |
| SCHEMBL3162433 | 0.73 | ALDH1A1 (0.43) | ESR2ESR1ALDH1A1GAAMAPT | |
| SCHEMBL29871375 | 0.73 | ALDH1A1 (0.43) | ESR2ESR1ALDH1A1GAAMAPT | |
| SCHEMBL19892266 | 0.71 | ALDH1A1 (0.46) | ESR2ESR1ALDH1A1MAPTHSP90AA1 | |
| SCHEMBL70722 | 0.71 | ALDH1A1 (0.46) | ESR2ESR1ALDH1A1MAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000056702-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2000-09-28 | — | — | WO | disclosed |