Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 11/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012733 | 0.90 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP2C9CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL6356136 | 0.90 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP2C9CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL7496961 | 0.89 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP2C9CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL7495170 | 0.88 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP2C9CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL6353230 | 0.86 | CYP3A4 (0.61) | SMN1; SMN2CYP2C9CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL6350950 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP2C9CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL6360390 | 0.84 | CYP3A4 (0.59) | SMN1; SMN2CYP2C9CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL6356150 | 0.84 | CYP3A4 (0.68) | SMN1; SMN2CYP2C9CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL7494111 | 0.81 | CYP3A4 (0.62) | SMN1; SMN2CYP2C9CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL6349099 | 0.81 | CYP3A4 (0.70) | SMN1; SMN2CYP2C9CYP3A4CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050154007-A1 | New compounds | AMIN KOSRAT (SE) | 2005-07-14 | — | — | US | disclosed |
| US-6790960-B2 | Compounds | ASTRAZENECA AB (SE) | 2004-09-14 | — | — | US | disclosed |
| US-20030220364-A1 | New compounds | AMIN KOSRAT (SE) | 2003-11-27 | — | — | US | disclosed |
| US-6579884-B1 | Compounds | ASTRAZENECA AB (SE) | 2003-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220364-A1 | New compounds | SLC10A2, GIPR, FABP2 | SMN1; SMN2 4309/4885CYP2C9 3074/4885CYP3A4 2404/4885 |
| US-20050154007-A1 | New compounds | SLC10A2, GIPR, FABP6 | SMN1; SMN2 4396/4885CYP2C9 3139/4885CYP3A4 2475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.