SCHEMBL6433962

SCHEMBL6433962

Cc1cc(C2CCNC(S(=O)(=O)C3(C(=O)O)CCN(C(=O)OC(C)(C)C)CC3)C2)ccc1-c1cccc(OCCO)n1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 8/20 0.52
MMP3 P08254 7/20 0.52
MMP1 P03956 2/20 0.52
MMP9 P14780 2/20 0.52
MMP14 P50281 2/20 0.52
JAK2 O60674 2/20 0.34
JAK3 P52333 2/20 0.34
PTK2 Q05397 2/20 0.34
GUCY1A1 Q02108 2/20 0.34
GUCY1B1 Q02153 2/20 0.34
MMP13 P45452 1/20 0.34
TP53 P04637 1/20 0.32
GPR119 Q8TDV5 3/20 0.32
CCNT1 O60563 1/20 0.32
PRMT5 O14744 2/20 0.31
WNT3A P56704 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6437634 0.85 MMP2 (0.63) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6436456 0.80 MMP2 (0.63) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6959147 0.80 MMP2 (0.66) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6959875 0.79 MMP2 (0.61) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6968340 0.75 MMP2 (0.63) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6968614 0.74 MMP2 (0.64) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6435284 0.72 MMP2 (0.63) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6433718 0.70 MMP2 (0.62) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6433723 0.70 MMP2 (0.64) MMP2MMP3MMP1MMP9MMP14
Hydrochloric Acid SCHEMBL6437678 0.70 MMP2 (0.62) MMP2MMP3MMP1MMP9MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050026836-A1 Composition for the treatment of damaged tissue DACK KEVIN NEIL (GB) 2005-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050026836-A1 Composition for the treatment of damaged tissue MMP1, SERPINE1, COL14A1 MMP2 19/4885MMP3 28/4885MMP1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.