Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.66 |
| ▸ | MMP3 | P08254 | 7/20 | 0.66 |
| ▸ | MMP1 | P03956 | 3/20 | 0.66 |
| ▸ | MMP9 | P14780 | 2/20 | 0.66 |
| ▸ | MMP14 | P50281 | 2/20 | 0.66 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.39 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.38 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | ADAM10 | O14672 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436456 | 0.93 | MMP2 (0.63) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6437634 | 0.93 | MMP2 (0.63) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6439869 | 0.92 | MMP2 (0.62) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6956221 | 0.90 | MMP2 (0.68) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6959875 | 0.89 | MMP2 (0.61) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6964593 | 0.88 | MMP2 (0.67) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6964678 | 0.88 | MMP2 (0.67) | MMP2MMP3MMP1MMP9MMP14 | |
| Hydrochloric Acid SCHEMBL6965337 | 0.87 | MMP2 (0.66) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6435951 | 0.86 | MMP3 (0.69) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6435947 | 0.86 | MMP3 (0.69) | MMP2MMP3MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181017-B1 | METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-04-16 | — | — | EP | claimed |