Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397346 | 0.87 | CA12 (0.30) | — | |
| SCHEMBL17937757 | 0.80 | CYP2A6 (0.40) | CYP2A6ALDH1A1RAB9AMAPTRXFP1 | |
| SCHEMBL5421307 | 0.79 | — | — | |
| SCHEMBL6436993 | 0.79 | ESR2 (0.32) | KDM4E | |
| SCHEMBL5421236 | 0.79 | — | — | |
| SCHEMBL10539487 | 0.78 | CYP2A6 (0.38) | CYP2A6ALDH1A1MAPK1ALOX15IDO1 | |
| SCHEMBL1115633 | 0.77 | CYP2A6 (0.42) | CYP2A6ALDH1A1RAB9AMAPTRXFP1 | |
| SCHEMBL5421459 | 0.77 | — | — | |
| SCHEMBL16062866 | 0.77 | — | — | |
| SCHEMBL384790 | 0.77 | ACHE (0.42) | ALDH1A1RAB9AMAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555901-A | Polishing composition | FUJIMI INC | 2016-05-04 | — | — | CN | disclosed |
| EP-1276807-B1 | CURABLE SILICONE RESIN COMPOSITION AND REACTIVE SILICON COMPOUNDS | DOW CORNING (US) | 2005-10-12 | — | — | EP | disclosed |
| US-6780471-B2 | USING CROSSLINKER WITH NONFLEXIBLE LINKAGE INCLUDING AT LEAST ONE P-ARYLENE MOIETY FOR SPATIAL SEPARATION; FLEXURAL STRENGTH, FRACTURE TOUGHNESS, MODULUS AND/OR MECHANICAL DAMPING | DOW CORNING CORPORATION | 2004-08-24 | — | — | US | disclosed |
| US-20030130389-A1 | Curable silicone resin composition and reactive silicon compounds | DOW CORNING LIMITED (GB) | 2003-07-10 | — | — | US | disclosed |
| EP-1276807-A1 | CURABLE SILICONE RESIN COMPOSITION AND REACTIVE SILICON COMPOUNDS | Dow Corning Corporation (US) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001083608-A1 | CURABLE SILICONE RESIN COMPOSITION AND REACTIVE SILICON COMPOUNDS | DOW CORNING CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |