Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916640 | 0.81 | CYP2A6 (0.38) | CYP2A6ALDH1A1IDO1ALOX15MAPK1 | |
| SCHEMBL17921304 | 0.78 | ACHE (0.40) | ALDH1A1 | |
| SCHEMBL6433976 | 0.78 | CYP2A6 (0.40) | CYP2A6ALDH1A1IDO1ALOX15MAPK1 | |
| SCHEMBL2394267 | 0.75 | ESR1 (0.39) | — | |
| SCHEMBL17922577 | 0.74 | CA1 (0.50) | ALDH1A1IDO1MAPK1 | |
| SCHEMBL2488130 | 0.73 | ESR1 (0.38) | — | |
| SCHEMBL2527239 | 0.73 | ESR1 (0.38) | — | |
| SCHEMBL28062850 | 0.73 | CYP2A6 (0.35) | CYP2A6ALDH1A1IDO1MAPK1 | |
| SCHEMBL16562804 | 0.73 | ALDH1A1 (0.48) | CYP2A6ALDH1A1ALOX15MAPK1 | |
| SCHEMBL6433575 | 0.73 | CYP2A6 (0.35) | CYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824982-A | Method for the cleavage of organic siloxanes, and products and applications thereof | HUELS TROISDORF AG (DE) | 1989-04-25 | — | — | US | disclosed |
| EP-0115772-B1 | PROCESS FOR THE SPLITTING OF ORGANOSILOXANES AND RESULTING PRODUCTS AND THEIR APPLICATIONS | HÜLS AKTIENGESELLSCHAFT (DE) | 1989-02-15 | — | — | EP | disclosed |
| EP-0115772-A2 | Process for the splitting of organosiloxanes and resulting products and their applications | HÜLS AKTIENGESELLSCHAFT (DE) | 1984-08-15 | — | — | EP | disclosed |