SCHEMBL6434019

SCHEMBL6434019

O=[Si]([O-])[O-].O=[Si]([O-])[O-].[Ca+2].[Ni+2]

nearest known ligand 0.00

Known targets — ChEMBL curated mechanism

GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1885164 0.94
SCHEMBL3577 0.94
SCHEMBL8006466 0.94
SCHEMBL2868962 0.94
SCHEMBL30507 0.94
SCHEMBL502684 0.94
SCHEMBL149311 0.94
SCHEMBL17675347 0.88
SCHEMBL914234 0.88
SCHEMBL9422162 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1131155-B1 CATALYST AND PROCESS FOR PREPARING 1,3-PROPANEDIOL SHELL INT RESEARCH (NL) 2005-08-17 EP disclosed
US-6342464-B1 MOLYBDENUM NICKEL SILICATE CATALYST SHELL OIL COMPANY 2002-01-29 US disclosed
EP-1131155-A1 CATALYST AND PROCESS FOR PREPARING 1,3-PROPANEDIOL SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2001-09-12 EP disclosed
WO-2000025914-A1 CATALYST AND PROCESS FOR PREPARING 1,3-PROPANEDIOL SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2000-05-11 WO disclosed
US-5945570-A Catalyst and process for preparing 1,3-propanediol SHELL OIL COMPANY 1999-08-31 US disclosed
US-4101449-A SINTERING ANICKEL OXIDE FUJIMI KENMAZAI KOGYO CO., LTD. (JP) 1978-07-18 US disclosed