SCHEMBL6434188

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL6434449	0.92	ACLY (0.48)	CYP2C9KMT2AMEN1ALDH1A1TP53
	SCHEMBL6434187	0.86	CYP2C9 (0.60)	CYP2C9KMT2AMEN1ALDH1A1TP53
	SCHEMBL6437969	0.77	PLAU (0.54)	CYP2C9KMT2AMEN1KDM4EPLG
	SCHEMBL6436460	0.76	PLAU (0.71)	CYP2C9KMT2AMEN1ALDH1A1TP53
	SCHEMBL6437758	0.76	PLAU (0.55)	KMT2AMEN1ALDH1A1SMN1; SMN2PLG
	SCHEMBL6437441	0.76	PLAU (0.57)	PLGPLAU
	Hydrochloric Acid SCHEMBL6433181	0.75	PLAU (0.70)	CYP2C9KMT2AMEN1ALDH1A1TP53
	SCHEMBL7369764	0.75	CYP2C9 (0.52)	CYP2C9KMT2AMEN1ALDH1A1TP53
	SCHEMBL7362086	0.75	PLAU (0.46)	PLGPLAU
	SCHEMBL6434181	0.74	CYP2C9 (0.52)	CYP2C9KMT2AMEN1ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.