Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 2/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30388675 | 0.88 | NUDT1 (0.50) | ALDH1A1PNPKDM4ENUDT1METAP2 | |
| SCHEMBL5632 | 0.88 | NUDT1 (0.50) | ALDH1A1PNPKDM4ENUDT1METAP2 | |
| Hydrochloric Acid SCHEMBL357697 | 0.86 | NUDT1 (0.48) | ALDH1A1PNPKDM4ENUDT1METAP2 | |
| Thioguanine SCHEMBL5607942 | 0.83 | PNP (0.47) | ALDH1A1PNPKDM4ENUDT1RXFP1 | |
| Guanine SCHEMBL1100665 | 0.83 | PNP (0.70) | ALDH1A1PNPKDM4EXDHHPGD | |
| Purine SCHEMBL29703771 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4ERXFP1METAP2METAP1 | |
| Purine SCHEMBL30862524 | 0.82 | — | — | |
| Purine SCHEMBL29365913 | 0.82 | — | — | |
| Purine SCHEMBL2120554 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4ERXFP1METAP2METAP1 | |
| Purine SCHEMBL3158 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014164-A1 | Triplex-forming oligonucleotides containing modified purines and their applications | ERITJA RAMON (ES) | 2005-01-20 | — | — | US | disclosed |