Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24451736 | 0.83 | ALDH1A1 (0.48) | XDHKIF11ALDH1A1MAPTGABRA1 | |
| SCHEMBL14721524 | 0.81 | KIF11 (0.48) | KIF11ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL7030477 | 0.81 | PARP1 (0.44) | XDHALDH1A1MAPTGABRA1GABRB2 | |
| SCHEMBL7975028 | 0.80 | AHR (0.52) | XDHKIF11ALDH1A1MAPTGABRA1 | |
| SCHEMBL12683843 | 0.76 | KIF11 (0.49) | XDHKIF11ALDH1A1MAPTGABRA1 | |
| Carbazole SCHEMBL29178543 | 0.72 | ALDH1A1 (0.54) | KIF11ALDH1A1MAPTGABRA1GABRB2 | |
| SCHEMBL29864765 | 0.71 | KIF11 (0.81) | KIF11ALDH1A1KDM4ECYP1A2AHR | |
| SCHEMBL278605 | 0.71 | KIF11 (0.81) | KIF11ALDH1A1KDM4ECYP1A2AHR | |
| SCHEMBL24727406 | 0.71 | KIF11 (0.55) | KIF11ALDH1A1GABRA1GABRB2KDM4E | |
| SCHEMBL173301 | 0.71 | ALDH1A1 (0.64) | XDHALDH1A1MAPTGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119491-A1 | 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof | SHEFFIELD, THE UNIVERSITY OF (GB) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119491-A1 | 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof | CBR3, OR10J3, ORC3 | XDH 3930/4885KIF11 3069/4885ALDH1A1 2970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.