⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20677323 | 0.85 | — | — | |
| SCHEMBL6435000 | 0.82 | — | — | |
| SCHEMBL9633053 | 0.78 | THRB (0.32) | — | |
| SCHEMBL6433037 | 0.77 | — | — | |
| SCHEMBL11517580 | 0.75 | ALDH1A1 (0.38) | — | |
| SCHEMBL3674773 | 0.73 | — | — | |
| SCHEMBL10723562 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL5053913 | 0.71 | — | — | |
| SCHEMBL6437515 | 0.71 | MAPT (0.50) | — | |
| SCHEMBL23112999 | 0.71 | THRB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160130268-A1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR INHIBITORS | PRINCIPIA BIOPHARMA INC. | 2016-05-12 | — | — | US | claimed |
| US-20220390458-A1 | FLUORESCENT PROBE AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-12-08 | — | — | US | disclosed |
| WO-2021058490-A2 | FLUORESCENT PROBE AND APPLICATIONS THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2021-04-01 | — | — | WO | disclosed |
| EP-3795643-A1 | FLUORESCENT PROBE AND APPLICATIONS THEREOF | Centre National de la Recherche Scientifique (FR) | 2021-03-24 | — | — | EP | disclosed |
| EP-1172400-B1 | THERMOPLASTIC RESIN FILM WITH SATISFACTORY PRINTABILITY | YUPO CORP (JP) | 2005-12-28 | — | — | EP | disclosed |
| US-6586106-B2 | Ink transfer, adhesion and aging stability, and being satisfactory in back ghost when offset printing using oxidation polymerization type ink is performed on both faces | YUPO CORPORATION (JP) | 2003-07-01 | — | — | US | disclosed |
| US-20020054991-A1 | Thermoplastic resin film satisfactory in printability | YUPO CORPORATION (JP) | 2002-05-09 | — | — | US | disclosed |
| EP-1172400-A1 | THERMOPLASTIC RESIN FILM WITH SATISFACTORY PRINTABILITY | Yupo Corporation (JP) | 2002-01-16 | — | — | EP | disclosed |
| EP-0019843-B1 | SISOMICIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES | BAYER AG (DE) | 1982-09-29 | — | — | EP | disclosed |
| US-4312859-A | ANTIBIOTICS, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-26 | — | — | US | disclosed |
| EP-0019843-A1 | Sisomicin derivatives, process for their preparation and their use as medicines | BAYER AG (DE) | 1980-12-10 | — | — | EP | disclosed |