Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29013338 | 0.82 | LMNA (0.42) | THRB | |
| SCHEMBL29013339 | 0.82 | LMNA (0.42) | THRB | |
| SCHEMBL29013305 | 0.82 | LMNA (0.42) | THRB | |
| SCHEMBL11345995 | 0.82 | AKR1B1 (0.38) | — | |
| SCHEMBL20677323 | 0.81 | — | — | |
| SCHEMBL11517580 | 0.81 | ALDH1A1 (0.38) | — | |
| SCHEMBL14655871 | 0.79 | LMNA (0.50) | — | |
| SCHEMBL6434759 | 0.78 | — | — | |
| SCHEMBL1986858 | 0.78 | SMN1; SMN2 (0.43) | THRB | |
| SCHEMBL6438507 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287341-B1 | RECTALLY ABSORBABLE FORM OF L-DOPA | MERCK & CO. INC. (US) | 1992-06-17 | — | — | EP | claimed |
| EP-0287341-A1 | Rectally absorbable form of L-dopa | MERCK & CO. INC. (US) | 1988-10-19 | — | — | EP | claimed |