Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14855299 | 0.91 | ALDH1A1 (0.64) | ALDH1A1LMNAHPGDSMN1; SMN2HTT | |
| SCHEMBL11915177 | 0.91 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDSMN1; SMN2HTT | |
| SCHEMBL12230601 | 0.89 | ALDH1A1 (0.56) | ALDH1A1LMNAHPGDSMN1; SMN2HTT | |
| SCHEMBL14403087 | 0.89 | ALDH1A1 (0.45) | ALDH1A1LMNAHPGDSMN1; SMN2HTT | |
| SCHEMBL17905782 | 0.88 | ALDH1A1 (0.43) | ALDH1A1LMNAHPGDSMN1; SMN2HTT | |
| SCHEMBL12882555 | 0.88 | TSHR (0.54) | ALDH1A1LMNAHPGDSMN1; SMN2HTT | |
| SCHEMBL12604863 | 0.84 | POLB (0.50) | ALDH1A1LMNAHPGDSAE1UBA2 | |
| SCHEMBL469386 | 0.84 | ALDH1A1 (0.72) | ALDH1A1LMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL11915176 | 0.83 | CYP3A4 (0.69) | ALDH1A1LMNAHPGDSMN1; SMN2HTT | |
| SCHEMBL17489435 | 0.83 | TSHR (0.63) | ALDH1A1LMNAHPGDSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4342473-A2 | COMPOUNDS USEFUL IN HIV THERAPY | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2024-03-27 | — | — | EP | disclosed |
| US-20240051972-A1 | Compounds Useful in HIV Therapy | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-02-15 | — | — | US | disclosed |
| US-11873310-B2 | Compounds useful in HIV therapy | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-01-16 | — | — | US | disclosed |
| US-11492361-B2 | Compounds useful in HIV therapy | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-11-08 | — | — | US | disclosed |
| US-20220119417-A1 | Compounds Useful in HIV Therapy | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-04-21 | — | — | US | disclosed |
| EP-2204408-B1 | POLYOLEFIN RESIN COMPOSITION | ADEKA CORP (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2014209934-A1 | THERMOPLASTIC POLYURETHANE AND ASSOCIATED METHOD AND ARTICLE | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-12-31 | — | — | WO | disclosed |
| US-8853443-B2 | Process for preparing an isocyanate | BASF SE (DE) | 2014-10-07 | — | — | US | disclosed |
| US-8853443-B2 | Process for preparing an isocyanate | BASF SE (DE) | 2014-10-07 | — | — | US | disclosed |
| EP-2367783-B1 | METHOD FOR PRODUCING AN ISOCYANATE | BASF SE (DE) | 2013-01-09 | — | — | EP | disclosed |
| US-4783500-A | ORGANO-SILICON,-TIN, OR -GERMANIUM INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-08 | — | — | US | disclosed |
| US-4711942-A | FROM ACRYLIC OR MALEIMIDE MONOMER AND ORGANOSILICON,-TIN, OR -GERMANIUM INITIATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-08 | — | — | US | disclosed |
| EP-0103968-B1 | FORTIFIER FOR EPOXY RESINS, METHOD FOR THE PREPARATION THEREOF AND FORTIFIED EPOXY RESIN COMPOSITIONS CONTAINING SAME | Canadian Patents and Development Limited Société Canadienne des Brevets et d'Exploitation Limitée (CA) | 1987-07-22 | — | — | EP | disclosed |
| US-4581428-A | Process for preparing \"living\" polymers using tetracoordinate organosilicon, organotin or organogermanium polymerization initiator with bifluoride ion source co-catalyst | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-04-08 | — | — | US | disclosed |
| US-4532259-A | Protect industrial material against attack by fungi, bacteria, insects | BAYER AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |
| EP-0145263-A1 | Living polymers and process for their preparation | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-06-19 | — | — | EP | disclosed |
| US-4480082-A | Epoxy resin fortifiers based on aromatic amides | CANADIAN PATENTS & DEVELOPMENT LIMITED (CA) | 1984-10-30 | — | — | US | disclosed |
| EP-0103968-A1 | Fortifier for epoxy resins, method for the preparation thereof and fortified epoxy resin compositions containing same | Canadian Patents and Development Limited Société Canadienne des Brevets et d'Exploitation Limitée (CA) | 1984-03-28 | — | — | EP | disclosed |
| EP-0083015-A1 | Bis-(fluoro and chloromethyl thioformamide), preparation and use thereof | BAYER AG (DE) | 1983-07-06 | — | — | EP | disclosed |
| US-3949559-A | Process for isolating aqueous brine layers in underground gas-storage caverns | BERGWERKSVERBAND GMBH (DT) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119417-A1 | Compounds Useful in HIV Therapy | CD4, CCR5, ABCB1 | ALDH1A1 424/4885LMNA 2214/4885HPGD 345/4885 |
| US-20240051972-A1 | Compounds Useful in HIV Therapy | CD4, CCR5, ABCB1 | ALDH1A1 424/4885LMNA 2214/4885HPGD 345/4885 |
| US-11873310-B2 | Compounds useful in HIV therapy | CD4, CCR5, ABCB1 | ALDH1A1 424/4885LMNA 2214/4885HPGD 345/4885 |
| US-11492361-B2 | Compounds useful in HIV therapy | CD4, CCR5, ABCB1 | ALDH1A1 474/4885LMNA 2648/4885HPGD 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.