⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570627 | 1.00 | — | — | |
| SCHEMBL4198189 | 0.84 | — | — | |
| SCHEMBL185293 | 0.81 | TSHR (0.31) | — | |
| SCHEMBL185294 | 0.81 | TSHR (0.31) | — | |
| SCHEMBL37014 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL37013 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL6667547 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL6435681 | 0.76 | DPP4 (0.31) | — | |
| SCHEMBL1660503 | 0.74 | CA2 (0.40) | — | |
| SCHEMBL10395138 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326901-B1 | ACYLPHOSPHINE OXIDE PHOTOINITIATORS IN METHACRYLATE CASTING RESINS | CIBA SC HOLDING AG (CH) | 2005-06-08 | — | — | EP | disclosed |
| EP-0982334-B1 | A process for producing polycondensable macromonomer | COUNCIL SCIENT IND RES (IN) | 2004-04-14 | — | — | EP | disclosed |
| US-20030164580-A1 | Acylphosphine oxide photoinitiators in methacrylate casting resins | CIBA SPECIALTY CHEMICALS CORP. | 2003-09-04 | — | — | US | disclosed |
| EP-1326901-A1 | ACYLPHOSPHINE OXIDE PHOTOINITIATORS IN METHACRYLATE CASTING RESINS | Ciba SC Holding AG (CH) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002022697-A1 | ACYLPHOSPHINE OXIDE PHOTOINITIATORS IN METHACRYLATE CASTING RESINS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-03-21 | — | — | WO | disclosed |
| EP-0982334-A1 | A process for producing polycondensable macromonomer | Council of Scientific and Industrial Research (IN) | 2000-03-01 | — | — | EP | disclosed |
| US-6022930-A | Process for producing polycondensable macromonomer | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2000-02-08 | — | — | US | disclosed |
| US-5324802-A | Method for bulk polymerizing methyl methacrylate | ROHM GMBH (DE) | 1994-06-28 | — | — | US | disclosed |
| EP-0519362-A1 | Process for preparing polymethylmethacrylate by mass polymerisation | RÖHM GMBH (DE) | 1992-12-23 | — | — | EP | disclosed |