SCHEMBL6435238

SCHEMBL6435238

C=CC(=O)NOS(=O)(=O)CC(C)C.[NaH]

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
TGM2 P21980 2/20 0.33
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1698197 0.98 TSHR (0.39) TSHRTGM2ALDH1A1MAPK1TDP1
SCHEMBL31435702 0.97 TSHR (0.38) TSHRTGM2ALDH1A1MAPK1TDP1
SCHEMBL10584159 0.86 TSHR (0.38) TSHRTGM2ALDH1A1MAPK1TDP1
SCHEMBL28866456 0.83 TSHR (0.36) TSHRTGM2ALDH1A1MAPK1TDP1
SCHEMBL28029618 0.81 TSHR (0.37) TSHRALDH1A1MAPK1TDP1
SCHEMBL4673569 0.80 TSHR (0.38) TSHRTGM2ALDH1A1MAPK1TDP1
SCHEMBL19457655 0.78 ZDHHC20 (0.41) TSHRALDH1A1MAPK1
SCHEMBL10714172 0.77 TSHR (0.35) TSHRTGM2ALDH1A1MAPK1TDP1
SCHEMBL28018293 0.77 TSHR (0.42) TSHRTGM2ALDH1A1MAPK1TDP1
SCHEMBL22318956 0.76 ZDHHC20 (0.42) TSHRALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118103023-A Retarder composition and dye set comprising same 莱雅公司 2024-05-28 CN disclosed
CN-113194722-B Antimicrobial mixtures containing 4- (3-ethoxy-4-hydroxyphenyl) butan-2-one and 4-hydroxyacetophenone, and compositions containing the same 莱雅公司 2023-05-05 CN disclosed
WO-2023072893-A1 USE OF HIGH MOLECULAR WEIGHT NARROW POLYDISPERSITY POLYMERS AS FLOCCULANTS OR VISCOSIFIERS BASF SE (DE) 2023-05-04 WO disclosed
US-11466101-B2 Self-invertible inverse latex comprising alkyl polyglycosides as an inverting agent and use thereof as a thickening agent for a detergent or cleaning formulation for industrial or domestic use SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2022-10-11 US disclosed
CN-114761528-A Biodegradable package containing water-soluble capsules 联合利华知识产权控股有限公司 2022-07-15 CN disclosed
CN-111479835-B Self-reversible inverse latex comprising an alkyl polyglycoside as inverse and use thereof as thickener for detergent or cleaning formulations for industrial or domestic use 化工产品开发公司SEPPIC 2021-11-26 CN disclosed
US-20200354655-A1 SELF-INVERTIBLE INVERSE LATEX COMPRISING ALKYL POLYGLYCOSIDES AS AN INVERTING AGENT AND USE THEREOF AS A THICKENING AGENT FOR A DETERGENT OR CLEANING FORMULATION FOR INDUSTRIAL OR DOMESTIC USE SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2020-11-12 US disclosed
CN-111479835-A Self-reversible inverse latex comprising an alkyl polyglycoside as inverse and use thereof as thickener for detergent or cleaning formulations for industrial or domestic use 化工产品开发公司SEPPIC 2020-07-31 CN disclosed
CN-111356431-A Self-reversible inverse latex comprising an alkyl polyglycoside as inverse, use thereof as thickener, and cosmetic composition comprising same 化工产品开发公司SEPPIC 2020-06-30 CN disclosed
US-20200087597-A1 Encapsulated Solid Enzyme Product NOVOZYMES A/S (DK) 2020-03-19 US disclosed
US-20030235604-A1 Renewable surface treatment of silicone medical devices with reactive hydrophilic polymers BAUSCH & LOMB INCORPORATED (US) 2003-12-25 US disclosed
CN-1461325-A Method of applying a polymeric lens coating BAUSCH & LOMB (US) 2003-12-10 CN disclosed
US-6638563-B2 Comprises dimethyacrylamide-octafluoropentylmethacrylate-glycidyl methacrylate for enhancing biocompatibility/ hydrophilicity of surfaces of silicone contact lenses (overnight and continuous wear) and medical implants BAUSCH & LOMB INCORPORATED 2003-10-28 US disclosed
US-6599559-B1 Biocompatible coating for hydrogel contact lens; comfortable for a longer period of time; tear wettable; oxygen permeable; long term continuous wear without adverse effects to cornea BAUSCH & LOMB INCORPORATED 2003-07-29 US disclosed
EP-1319037-A1 METHOD FOR APPLYING POLYMERIC LENS COATING BAUSCH & LOMB INCORPORATED (US) 2003-06-18 EP disclosed
US-20030068433-A1 Method for applying polymeric lens coating BAUSCH & LOMB INCORPORATED 2003-04-10 US disclosed
EP-1268621-A1 SURFACE TREATMENT OF SILICONE MEDICAL DEVICES BAUSCH & LOMB INCORPORATED (US) 2003-01-02 EP disclosed
WO-2002024793-A1 METHOD FOR APPLYING POLYMERIC LENS COATING BAUSCH & LOMB INCORPORATED (US) 2002-03-28 WO disclosed
WO-2001074932-A1 SURFACE TREATMENT OF SILICONE MEDICAL DEVICES BAUSCH & LOMB INCORPORATED (US) 2001-10-11 WO disclosed
CN-1141065-A Ionically conductive agent, system for cathodic protection of galvanically active metals, and method and apparatus for using same MINNESOTA MINING & MFG (US) 1997-01-22 CN disclosed