Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 6/20 | 0.47 |
| ▸ | ANO2 | Q9NQ90 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3913445 | 0.90 | ALDH1A1 (0.59) | KMT2ATP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6436355 | 0.84 | KMT2A (0.54) | KMT2AMEN1NOD1TP53ANO1 | |
| SCHEMBL3911867 | 0.82 | TLR2 (0.54) | KMT2ATP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL3914193 | 0.82 | TLR2 (0.67) | KMT2ATP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL3914457 | 0.82 | TLR2 (0.53) | KMT2ATP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6456408 | 0.80 | ALDH1A1 (0.60) | KMT2AMEN1NOD1SMN1; SMN2MAPT | |
| SCHEMBL6438921 | 0.80 | KMT2A (0.52) | KMT2AMEN1GAANOD1RAB9A | |
| SCHEMBL6441582 | 0.80 | CNR2 (0.49) | KMT2AMEN1NOD1TP53SMN1; SMN2 | |
| SCHEMBL3913979 | 0.79 | TLR2 (0.58) | KMT2AGAATP53SMN1; SMN2MAPT | |
| SCHEMBL6465710 | 0.79 | KMT2A (0.49) | KMT2AMEN1GAANOD1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492783-A1 | 4,5,6,7-TRETRAHYDROBENZO(B) THIOPHENE DERIVATIVES AND METHODS FOR MEDICAL INTERVENTION AGAINST MYCROBACTERIAL INFECTIONS | Axxima Pharmaceuticals AG (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003084947-A1 | 4,5,6,7-TRETRAHYDROBENZO[B] THIOPHENE DERIVATIVES AND METHODS FOR MEDICAL INTERVENTION AGAINST MYCROBACTERIAL INFECTIONS | AXXIMA PHARMACEUTICALS AG (DE) | 2003-10-16 | — | — | WO | disclosed |