Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 4/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPRB | P23467 | 1/20 | 0.45 |
| ▸ | PTPRE | P23469 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3914099 | 0.88 | TLR2 (0.54) | CNR1CNR2GAAKDM4EMAPT | |
| SCHEMBL6438921 | 0.83 | KMT2A (0.52) | KMT2AMEN1CNR2NOD1ABCC1 | |
| SCHEMBL6437614 | 0.83 | KMT2A (0.51) | KMT2AMEN1CNR2NOD1ABCC1 | |
| SCHEMBL6438040 | 0.81 | KMT2A (0.51) | KMT2AMEN1NOD1GAAKDM4E | |
| SCHEMBL6435397 | 0.79 | KMT2A (0.53) | KMT2AMEN1CNR2NOD1GAA | |
| SCHEMBL6436355 | 0.79 | KMT2A (0.54) | KMT2AMEN1CNR2NOD1MAPT | |
| SCHEMBL3914021 | 0.79 | TLR2 (0.57) | CNR1CNR2GAAKDM4EMAPT | |
| SCHEMBL3914029 | 0.77 | TLR2 (0.55) | CNR1CNR2KDM4EMAPT | |
| SCHEMBL3917748 | 0.77 | TLR2 (0.55) | CNR1CNR2GAAKDM4EMAPT | |
| SCHEMBL6456408 | 0.77 | ALDH1A1 (0.60) | KMT2AMEN1CNR2NOD1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492783-A1 | 4,5,6,7-TRETRAHYDROBENZO(B) THIOPHENE DERIVATIVES AND METHODS FOR MEDICAL INTERVENTION AGAINST MYCROBACTERIAL INFECTIONS | Axxima Pharmaceuticals AG (DE) | 2005-01-05 | — | — | EP | claimed |
| WO-2003084947-A1 | 4,5,6,7-TRETRAHYDROBENZO[B] THIOPHENE DERIVATIVES AND METHODS FOR MEDICAL INTERVENTION AGAINST MYCROBACTERIAL INFECTIONS | AXXIMA PHARMACEUTICALS AG (DE) | 2003-10-16 | — | — | WO | claimed |