SCHEMBL6435398

SCHEMBL6435398

O=C(O)C1=C(O)[C@H](O)CC=C1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18403605 1.00 ACMSD (0.30) ACMSD
SCHEMBL16368527 0.70
SCHEMBL13248855 0.67 MAPT (0.31)
SCHEMBL13183766 0.67
SCHEMBL25469170 0.66 KDM4E (0.30)
SCHEMBL818288 0.64 ALDH1A1 (0.35)
SCHEMBL27261830 0.64 MAPT (0.33)
SCHEMBL1399146 0.62
SCHEMBL7595763 0.62
SCHEMBL15390843 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1313870-B1 METHOD FOR THE IMPROVED PRODUCTION AND ISOLATION OF TRANS-DIHYDROXYCYCLOHEXADIENE CARBOXYLIC ACIDS AND/OR DERIVATIVES THEREOF AND A GENETICALLY MODIFIED ORGANISM SUITABLE FOR THE ABOVE FORSCHUNGSZENTRUM JUELICH GMBH (DE) 2005-09-21 EP claimed
US-20030224495-A1 Method for the improved production and isolation of trans-dihydroxycyclohexadiene carboxylic acids and/or derivatives thereof and genetically modified organism suitable therefor DSM BIOTECH GMBH (DE) 2003-12-04 US claimed
US-20030224495-A1 Method for the improved production and isolation of trans-dihydroxycyclohexadiene carboxylic acids and/or derivatives thereof and genetically modified organism suitable therefor DSM BIOTECH GMBH (DE) 2003-12-04 US disclosed